Results 91 to 100 of about 202,266 (264)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Statistical Analysis of Polycyclic Aromatic Hydrocarbons as a Tracer of Anomalous Microwave Emission Using DIRBE Data

open access: yesThe Astrophysical Journal
We use archival data from the Diffuse Infrared Background Experiment (DIRBE) to map the polycyclic aromatic hydrocarbon (PAH) 3.3 μ m emission feature and analyze its correlation with anomalous microwave emission (AME) in 98 compact sources identified by
Danielle Sponseller   +3 more
doaj   +1 more source

The X-Ray Emission Reveals the Coronal Activities of Semi-detached Binaries

open access: yesThe Astrophysical Journal
Abstract X-ray emission is an important tracer of stellar magnetic activity. We carried out a systematic correlation analysis for the X-ray luminosity log L
Junhui Liu, Jianfeng Wu
openaire   +3 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Multiple Jets in the Bursting Protostar HOPS 373SW

open access: yesThe Astrophysical Journal
We present the outflows detected in HOPS 373SW, a protostar undergoing a modest 30% brightness increase at 850 μ m. Atacama Large Millimeter/submillimeter Array observations of shock tracers, including SiO 8–7, CH _3 OH 7 _k –6 _k , and ^12 CO 3–2 ...
Seokho Lee   +4 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

A Novel Centralized Allocation Data Envelopment Analysis Model for Carbon Emission Allocation Under a Heterogeneous Abatement Cost: Application Within the Chinese Industrial Sector

open access: yesMathematics
This paper presents a mathematical approach to analyzing carbon abatement costs and the allocation of carbon emission allowances in China’s industrial sectors.
Xiaohong Liu   +3 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

An Iridium Complex as Bidentate Halogen Bond‐Based Anion Receptor Featuring an IncreasedOptical Response

open access: yesChemistryOpen
We present a luminescent Ir(III) complex featuring a bidentate halogen bond donor site capable of strong anion binding. The tailor‐made Ir(III)(L)2 moiety offers a significantly higher emission quantum yield (8.4 %) compared to previous Ir(III)‐based ...
Robin Kampes   +8 more
doaj   +1 more source

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