Results 91 to 100 of about 4,447 (297)

Imagem-afeção no filme “O Regresso”

open access: yesSignificação: Revista de Cultura Audiovisual, 2021
A geração de significados de imagens cinematográficas é o contexto deste artigo, que tem como objetivos contribuir para a compreensão do conceito de imagem-afeção – uma modalidade de imagemmovimento – e sugerir estratégias de análise fílmica. Para tanto,
Maria Ogécia Drigo
doaj  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Esthétique du brouillon et des compositions déjetées. L’élégance-crasse de Cy Twombly par Roland Barthes

open access: yesCaptures
Cy Twombly a mis en oeuvre une esthétique du brouillon éblouissante, réalisant des dessins hors genre qui supposaient d’abandonner les conventions, de libérer l’usage des couleurs et de se débarrasser des couches d’habitudes durcies par l’apprentissage ...
Maud Hagelstein
doaj   +1 more source

La théorie linguistique de Gustave Guillaume scrutée dans une perspective énactive

open access: yesSignifiances (Signifying), 2017
Aux successeurs de Gustave Guillaume on a souvent reproché une forme d’opportunisme qui, dans sa théorie linguistique, les a successivement conduits à retrouver certains traits de la grammaire générative, puis de l’énonciationnisme et de la sémantique ...
Francis Tollis
doaj   +1 more source

Revenances

open access: yesCalenda, 2015
Un revenant, c’est un disparu qui revient pour réclamer son dû. Le revenant personnifie, en ce sens, le symptôme d’un malaise que la communauté ne peut plus retenir ni contenir : celle-ci est sommée, par l’apparition, d’intégrer symboliquement, suivant un ensemble réglé de rituels et un effort collectif de remémoration, ses réquisits.
openaire   +1 more source

Editors Introduction to Revenant Journal: Occult Edition [PDF]

open access: yes
The introduction to issue 12 of Revenant Journal.
Howard, Jeff, Poole, Simon
core  

Capital Revenge: Ideologiekritik and The Revenant

open access: yes, 2016
Though superficially The Revenant is an expertly written, acted, and directed new age Western about one man\u27s wild quest for revenge. It is all of those things to be sure, but this critical review essay goes deeper and explores the ideological ...
Bryant W Sculos, Sculos, Bryant W
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Un "Revenant" des Camps de la Mort

open access: yes, 1994
Boullard Bernard. Un "Revenant" des Camps de la Mort. In: Études Normandes, 43e année, n°1, 1994. Trois Normands.
Boullard, Bernard
core  

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