Results 51 to 60 of about 249 (238)
Dom Augustin Calmet wrote one of the most important treaties of the 18th century, the Traité sur les Apparitions des Esprits, et sur les Vampires, ou les Revenans de Hongrie, de Moravie, &c. (1746).
Carme Agustí Aparisi
doaj
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Mouth-Deposited Coins in Medieval Burials The intentionally deposited coin in a late medieval grave in the ruins of St Mary's Church in Tønsberg raised issues such as: how common was it to be buried with coins in the medieval period, and who and why ...
Hanne Ekstrøm Jordahl
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The role of mirabilia in literature produced by courtier clerics in 12th century England
The role of mirabilia in literature produced by courtier clerics in 12th century England The purpose of this paper is to prove that the marvelous phenomena described in the works of Gerald of Wales and Walter Map played a double, religious and ...
Idalia Smoczyk-Jackowiak
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Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Projevy nepietního způsobu ukládání mrtvých u středověkých populací
In this study is collected a number of existing pieces of knowledge about substandard treatment with the dead bodies. There are also discussed the reasons which led the society to these acts. These persons were the revenants (e.
Lucie Čulíková
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We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The paper examines some of the Gothic features used in character development in William Faulkner’s Absalom, Absalom! and Toni Morrison’s Beloved, and explores how the two novels complement each other to form a comprehensive picture of the American South ...
Artea Panajotović
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