Results 61 to 70 of about 249 (238)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Clean by Nature. Lively Surfaces and the Holistic-Systemic Heritage of Contemporary Bionik.
communication +1, 2014 This paper addresses questions regarding the prospering field of Bionik in Germany. Its starting point is the wide spread assumption that universal functional principles exist in nature and that these ‘solutions’ can be transferred into technological ...
Jan Mueggenburg
doaj +1 more source
liquid blackness, 2022 Abstract Through sensitive engagement with the experimental films of Arthur Jafa, the flex choreography of Storyboard P, and performance of #BlackLivesMatter protests, this essay submits revenant motion as a concept through which to think about black being and phenomenology in this era.
openaire +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Les revenants et leurs liens avec les êtres et les objets « transitionnels »
Conserveries Mémorielles, 2016 There exists spatial symbolism (village-cemetery) and temporary symbolism (day-night) linked to the world of the dead, they intermingle and they are in movement. They also result of a successful transmission through childhood socialization. Sometimes the
María Dolores Muñoz Jiménez
doaj
The Texts and The Sculptures/Monuments (On the Poem The City by Š. Strážay and Its Associated Background) [PDF]
Slovenska Literatura, 2014 The text is an act of reading the poem The City from the collection The Interier (1992) by Štefan Strážay. The motif of covered sculptures is a poem set at the turn of the years 1989 – 1990. The article tracks the motifs of bad signs, spectres, revenants.
Fedor Matejov
doaj
Between, 2017 Abrstact (english) Contemporary realistic fiction sometimes includes features which echo ancient ghost tales. Some characters come back after their death, other experience great difficulties inhabiting the present, as if they were haunted.
Catherine Grall
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
[Understanding and guidelines for the management of antenatal diagnosis of diaphragmatic hernia: prognostic factors]. [PDF]
Pan Afr Med J, 2021 Attar I +4 more
europepmc +1 more source