Results 41 to 50 of about 669,579 (283)

Asymmetric and non linear adjustment in the revenue expenditure models [PDF]

open access: yes, 2002
The purpose of this paper is to empirically analyse the revenue-expenditure models of public finance by considering the possibility of non-linear and asymmetric adjustment.
Legrenzi, G, Milas, C
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Automated Revenue Prediction Modeling

open access: yes, 2020
RTI International has built a financial forecasting tool that we call Revenue Prediction Model (RPM). RPM ingests financial data from multiple databases, cleans the data, performs forecasting through cascading machine learning models, and generates daily reports in an interactive web dashboard that illustrates forecasted financial metrics for projects ...
openaire   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

THE IMPACT OF E-COMMERCE IN ON-LINE BUSINESS

open access: yesJurnal Analisis Bisnis Ekonomi, 2008
This research paper has aimed to-Commerce the first and the second waves, to find out the important role of E-Commerce in business, and to predict the future of E-Commerce. Those there issues will be the limination in this research paper. Since this is a
Rayna Kartika
doaj  

Modeling Tax Revenue Determinants: The Case of Visegrad Group Countries

open access: yesEconomies
This article provides panel data estimations of the tax revenue determinants in VG (Visegrad Group) countries (the Czech Republic, Hungary, Poland, and Slovakia) for the period 1994–2023.
Jadranka Đurović Todorović   +4 more
doaj   +1 more source

Tax rate to maximize the revenue: Laffer curve for the Czech Republic

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012
The aim of this article is to model the relationship between the rate of personal income tax and the revenue it generates, and to derive a tax rate that would maximize this revenue within the Czech Republic, using methodologies described in earlier works
Michal Karas
doaj   +1 more source

A Game-theoretic Framework for Revenue Sharing in Edge-Cloud Computing System

open access: yes, 2018
We introduce a game-theoretic framework to ex- plore revenue sharing in an Edge-Cloud computing system, in which computing service providers at the edge of the Internet (edge providers) and computing service providers at the cloud (cloud providers) co ...
Cao, Zhi   +3 more
core   +1 more source

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