Results 51 to 60 of about 669,579 (283)
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
This research explores the dynamic relationship between SIO (Strategic Income Optimization), RPM (Revenue Precision Management), SFM (Strategic Financial Management), IRS (Integrated Revenue Strategy), RDC (Revenue-Driven Culture), and FCC (Financial ...
Enkeleda Lulaj
doaj +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Police Killings and Municipal Reliance on Fine-and-Fee Revenue
High-profile police killings in the United States have drawn attention to how municipalities generate revenue through citations and arrests. This article investigates whether killings by police are more frequent in places that rely on fine-and-fee ...
Brenden Beck
doaj +1 more source
The Fiscal Regime Comparison of IRAN`s New Petroleum Contract (IPC) with Buy-Back Model: The Case study of Phases 4 & 5 of the South Pars Gas Field [PDF]
IRAN`s new petroleum contract is a new generation of service contract which aimed to fix bugs from Buy-Back model. In this model some incentives have inserted to increase contractors' motivations. In this study, we consider fiscal differences and revenue
Hadi Dibavand +4 more
doaj +1 more source
Growth and income distributions in four EU economies [PDF]
Dynamic multi-sectoral and multi-household general equilibrium models are constructed to show how the economies of Germany, France, Spain and the United Kingdom will evolve from 2006 to 2090.
Bhattarai, Keshab
core +1 more source
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst +4 more
wiley +1 more source
Advertising-based revenue model in digital media market
In the case of advertising-based revenue model, a company creates a digital media product, attracts interaction and engagement of users and then sells access to this audience to advertisers.
Alona Bekh
doaj

