Results 141 to 150 of about 599,451 (313)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Tricuspid Regurgitation-Induced Shunt Reversal Leading to Paradoxical Embolic Stroke [PDF]
Cheng-Hao Jacky Chen +3 more
openalex +1 more source
Reversal of epidural morphine-induced respiratory depression and pruritus with nalbuphine [PDF]
, 1988 John Penning +2 more
openalex +1 more source
Can machine learning reveal precursors of reversals of the geomagnetic axial dipole field?
, 2022 Kyle Gwirtz +5 more
openalex +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
The neural basis of reversal learning: An updated perspective
Neuroscience, 2017 A. Izquierdo +4 more
semanticscholar +1 more source
Supercoiling, knotting and replication fork reversal in partially replicated plasmids [PDF]
, 2002 Leticia Olavarrieta
openalex +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Magnetic reversal in perpendicularly magnetized antidot arrays with intrinsic and extrinsic defects [PDF]
, 2019 Michał Krupiński +3 more
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source