Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Visual learning performance in free-flying honey bees is independent of sucrose and light responsiveness and depends on training context. [PDF]
Kuklovsky V +3 more
europepmc +1 more source
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Reversal of neuromuscular blockade after coronary artery bypass grafting: a randomized control trial. [PDF]
Ellison MB +6 more
europepmc +1 more source
Body composition assessment by artificial intelligence can be a predictive tool for short-term postoperative complications in Hartmann’s reversals [PDF]
Reshi Suthakaran +8 more
openalex +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Functional Reversal as a Feasible Option for Malnutrition in Patients With Hyper-Response Following Roux-en-Y Gastric Bypass: A Case Report. [PDF]
Sánchez Muñoz MP +4 more
europepmc +1 more source
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Structural Reversibility of Optic-Disc Cupping in Glaucoma: Pathophysiology, Imaging Assessment, and Clinical Implications. [PDF]
Roberti G +5 more
europepmc +1 more source
PATTERN OF CHANGE OF BRONCHOMOTOR TONE FOLLOWING REVERSAL OF NEUROMUSCULAR BLOCKADE
Judith Hammond +2 more
openalex +1 more source

