Results 71 to 80 of about 599,451 (313)

Reversing anticoagulant effects of novel oral anticoagulants: role of ciraparantag, andexanet alfa, and idarucizumab

open access: yesVascular Health and Risk Management, 2016
Tiffany Y Hu,1 Vaibhav R Vaidya,2 Samuel J Asirvatham2,31Mayo Medical School, 2Division of Cardiovascular Diseases, Department of Internal Medicine, 3Department of Pediatrics and Adolescent Medicine, Mayo Clinic, Rochester, MN, USAAbstract: Novel oral ...
Hu TY, Vaidya VR, Asirvatham SJ
doaj  

Effect of a low-calorie diet on restoration of normoglycemia in obese subjects with type 2 diabetes

open access: yesIndian Journal of Endocrinology and Metabolism, 2017
Introduction: Type 2 diabetes mellitus (T2DM) is considered to be an inevitably progressive disease. Complex therapies add to the financial and psychological burden.
Anjali Amit Bhatt   +9 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Bölge Adliye Mahkemelerinin Bozma Kararlarının Yokluk Kavramı ile Birlikte Değerlendirilmesi

open access: yesAnadolu Üniversitesi Hukuk Fakültesi Dergisi
Kelime anlamı itibarıyla yeniden başlamak veya sözün başı anlamlarıyla özdeşleşen istinaf kavramı, iç hukuk sistemimizde ilk derece mahkemeleri tarafından verilen kararların ilgilerin istemi üzerine bir üst mahkeme tarafından hem hukuken hem de maddi ...
Metin Kaplan
doaj   +1 more source

THE EFFECT OF ERYTHROPOIETIN SUPPLEMENTATION ON SPERM MOTILITY AND MORPHOLOGY IN WISTAR RAT AFTER LIGATION RELEASE OF THE VAS DEFERENS

open access: yesJurnal Urologi Indonesia, 2019
Objective: The patency rates after vasectomy reversal ranges from 71-97%, but there is 26-72% possibility of persistent infertility. Dysfunction or obstruction of the epididymis and oxidative stress are thought to be the important cause of male ...
Aditya Pramanta   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Cup Reversal in a Steroid Responder Post-Trabeculectomy

open access: yesDelhi Journal of Ophthalmology, 2019
An 18 year old male presented with diminution of vision in right eye since 4 days. Fundus of the right eye examination revealed a cup disc ratio of 0.4:1 and occlusion of superior and inferior branch retinal vein.
Jayamadhury Gudimetla   +5 more
doaj   +1 more source

Separating Probability and Reversal Learning in a Novel Probabilistic Reversal Learning Task for Mice

open access: yesFrontiers in Behavioral Neuroscience, 2020
The exploration/exploitation tradeoff – pursuing a known reward vs. sampling from lesser known options in the hope of finding a better payoff – is a fundamental aspect of learning and decision making.
Jeremy A. Metha   +15 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

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