Results 211 to 220 of about 178,854 (310)

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Pharmaceutical, clinical, and resistance information on doravirine, a novel non-nucleoside reverse transcriptase inhibitor for the treatment of HIV-1 infection. [PDF]

Drugs Context, 2020
Pham HT, Xiao MA, Principe MA, Wong A, Mesplède T.   +4 more
europepmc   +1 more source

Structural Basis of HIV-1 Inhibition by Nucleotide-Competing Reverse Transcriptase Inhibitor INDOPY-1. [PDF]

J Med Chem, 2019
Ruiz FX, Hoang A, Das K, Arnold E.
europepmc   +1 more source

Very high baseline HIV viremia impairs efficacy of non-nucleoside reverse transcriptase inhibitor-based ART: a long-term observation in treatment-naïve patients. [PDF]

Infect Dis Poverty, 2020
Chen S, Han Y, Song XJ, Li YL, Zhu T, Lu HZ, Tang XP, Zhang T, Zhao M, He Y, He SH, Wang M, Li YZ, Huang SB, Li Y, Liu J, Cao W, Li TS.   +17 more
europepmc   +1 more source

A recombinant retroviral system for rapid in vivo analysis of human immunodeficiency virus type 1 susceptibility to reverse transcriptase inhibitors [PDF]

, 1997
Chaofu Shi, John W. Mellors
openalex   +1 more source

Efavirenz Has the Highest Anti-Proliferative Effect of Non-Nucleoside Reverse Transcriptase Inhibitors against Pancreatic Cancer Cells

, 2015
Markus Hecht, Sonja Erber, Thomas Harrer, Hartwig Klinker, Thomas Roth, Hans Parsch, Nora Fiebig, Rainer Fietkau, Luitpold Distel   +8 more
openalex   +2 more sources

Virtual screening, molecular docking studies and DFT calculations of FDA approved compounds similar to the non-nucleoside reverse transcriptase inhibitor (NNRTI) efavirenz. [PDF]

Heliyon, 2020
Jordaan MA, Ebenezer O, Damoyi N, Shapi M.   +3 more
europepmc   +1 more source

Low Cerebrospinal Fluid Concentrations of the Nucleotide HIV Reverse Transcriptase Inhibitor, Tenofovir

, 2012
Brookie M. Best, Scott Letendre, Peter J. Koopmans, Steven S. Rossi, David B. Clifford, Ann C. Collier, Benjamin B. Gelman, Christina M. Marra, Justin C. McArthur, J. Allen McCutchan, Susan Morgello, David M. Simpson, Edmund V. Capparelli, Ronald J. Ellis, Igor Grant   +14 more
openalex   +2 more sources

Epigenetic inflammatory memory and periodontal disease: Mechanisms and clinical significance for comorbidities

Journal of Periodontology, EarlyView.
Abstract Historically, immunological memory was considered an exclusive feature of adaptive immunity. However, innate immune cells have recently been shown to record and maintain epigenetically imprinted memory of earlier infectious or inflammatory challenges.
George Hajishengallis
wiley   +1 more source