Results 91 to 100 of about 2,625,760 (300)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
On a more accurate Hardy-Mulholland-type inequality
Journal of Inequalities and Applications, 2017 By using the way of weight coefficients, the technique of real analysis, and Hermite-Hadamard’s inequality, a more accurate Hardy-Mulholland-type inequality with multi-parameters and a best possible constant factor is given.
Bicheng Yang, Qiang Chen
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Bisimulations and Reversibility
Concurrency and causality can be expressed within a labelled transition system by exploiting reversibility of transitions. It is natural to ask what behavioural equivalences can be captured by bisimulations in the reversible setting. In this paper we work with keyed configuration structures and CCS K, establish an operational correspondence between the
Clément Aubert +2 more
openaire +2 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The sharp A(p) constant for weights in a reverse-Holder class [PDF]
, 2009 Coifman and Fefferman established that the class of Muckenhoupt weights is equivalent to the class of weights satisfying the "reverse Holder inequality". In a recent paper V.
Dindos, Martin; id_orcid, Wall, Treven
core
A more accurate half-discrete Hardy-Hilbert-type inequality with the logarithmic function
Journal of Inequalities and Applications, 2017 By means of the weight functions, the technique of real analysis and Hermite-Hadamard’s inequality, a more accurate half-discrete Hardy-Hilbert-type inequality related to the kernel of logarithmic function and a best possible constant factor is given ...
Aizhen Wang, Bicheng Yang
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source