Results 31 to 40 of about 1,985,009 (249)

Results of the Childhood Cancer and Leukaemia Group's United Kingdom Relapsed Wilms Tumour Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The United Kingdom relapsed Wilms tumour (UKW‐R) trial aimed to improve the historically low survival rates after relapse of Wilms tumour (WT) through a prospective national risk‐stratified protocol. The trial also evaluated efficacy and toxicity of high‐dose melphalan.
Sucheta J. Vaidya, Veronica Moroz, Juliet Hale, Vesna Pavasovic, Rachel Hobson, Patricia Sartori, Daniel Saunders, Mark Powis, Gordan M. Vujanic, Stephen Baker, Kathy Pritchard‐Jones   +10 more
wiley   +1 more source

Pollution source apportionment and health risk assessment of VOCs in automobile gearbox remanufacturing facilities

Scientific Reports
The progress of the transmission remanufacturing industry is in line with the development requirements of the circular economy, but its environmental pollution problems are easily ignored.
Zhuowen Wang, Ruixue Wang, Yuqing Tang, Chenglong Zhang   +3 more
doaj   +1 more source

Rigorous Analysis of the Quasi-Steady-State Assumption in Enzyme Kinetics

Mathematics, 2022
We study, from a purely quantitative point of view, the quasi-steady-state assumption for the fundamental mathematical model of the general enzymatic reaction. In particular, (i) we introduce a simple, yet generic, algorithm for the proper scaling of the
Vasiliki Bitsouni, Nikolaos Gialelis, Ioannis G. Stratis   +2 more
doaj   +1 more source

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman, Madeleine King, Rajen Mody, Sara‐Jane Onyeama, Araz Marachelian, Thomas Cash, Sara M. Federico, Meaghan Granger, Ami V. Desai, Suzanne Shusterman, Jennifer H. Foster, Elizabeth Sokol, Chelsee Greer, Keri Streby, Holly J. Meany, Kieuhoa T. Vo, Margaret E. Macy, Rochelle Bagatell   +17 more
wiley   +1 more source

A histone H3K9 methyltransferase Dim5 mediates repression of sorbicillinoid biosynthesis in Trichoderma reesei

Microbial Biotechnology, 2022
Sorbicillinoids (also termed yellow pigment) are derived from either marine or terrestrial fungi, exhibit various biological activities and therefore show potential as commercial products for human or animal health.
Lei Wang, Jialong Liu, Xiaotong Li, Xinxing Lyu, Zhizhen Liu, Hong Zhao, Xiangying Jiao, Weixin Zhang, Jun Xie, Weifeng Liu   +9 more
doaj   +1 more source

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Emerging Significance of Ginsenosides as Potentially Reversal Agents of Chemoresistance in Cancer Therapy

Frontiers in Pharmacology, 2021
Chemoresistance has become a prevalent phenomenon in cancer therapy, which alleviates the effect of chemotherapy and makes it difficult to break the bottleneck of the survival rate of tumor patients.
Jin-Feng Xu, Yan Wan, Fei Tang, Lu Chen, Yu Yang, Jia Xia, Jiao-Jiao Wu, Hui Ao, Hui Ao, Cheng Peng   +9 more
doaj   +1 more source

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source

On a more accurate Hardy-Mulholland-type inequality

Journal of Inequalities and Applications, 2016
By using weight coefficients, technique of real analysis, and Hermite-Hadamard’s inequality, we give a more accurate Hardy-Mulholland-type inequality with multiparameters and a best possible constant factor related to the beta function.
Bicheng Yang, Qiang Chen
doaj   +1 more source

A new reverse half-discrete Hilbert-type inequality with one partial sum involving one derivative function of higher order

Open Mathematics, 2023
In this article, a new reverse half-discrete Hilbert-type inequality with one partial sum involving one derivative function of higher order is obtained, by using the weight functions, the mid-value theorem, and the techniques of real analysis.
Liao Jianquan, Yang Bicheng
doaj   +1 more source