Results 161 to 170 of about 113,812 (280)
Regulation of human CETP gene expression
Journal of Lipid Research, 2003 Cholesteryl ester transfer protein (CETP) is a key factor in plasma reverse cholesterol transport and is implicated in the pathophysiology of atherogenic dyslipidemia.
Wilfried Le Goff +4 more
doaj
Overexpression of Human 15( S )-Lipoxygenase-1 in RAW Macrophages Leads to Increased Cholesterol Mobilization and Reverse Cholesterol Transport [PDF]
, 2009 Ginny L. Weibel +5 more
openalex +1 more source
Advanced Science, EarlyView.This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong +5 more
wiley +1 more source
Lipid metabolism in pancreatic cancer: emerging roles and potential targets
Cancer Communications, Volume 42, Issue 12, Page 1234-1256, December 2022., 2022 Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin +6 more
wiley +1 more source
Advanced Science, EarlyView.Liver fibrosis is a growing global health burden with no specific treatment. HSC activation is the predominant driver of liver fibrogenesis and the current focus in antifibrotic drug discovery. This study identifies autocrine GDF10 activates BMPR2/ALK3‐SMAD1/5/8‐SMAD7 pathway to counteract the TGF‐β‐SMAD2/3 pathway in HSCs, thereby inhibiting HSC ...
Yinliang Zhang +16 more
wiley +1 more source
Cancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022 Abstract Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome
Khaled S. Allemailem +6 more
wiley +1 more source
Imaging‐Guided Microscale Photothermal Stereolithography Bioprinting
Advanced Science, EarlyView.This work establishes imaging‐guided microscale photothermal stereolithography bioprinting, achieving microscale photothermal aqueous printing for the first time. Key innovations include novel imaging‐guided stereolithography, unique NIR‐II photothermal initiator, and new bioink with viscosity modifier.
Jingyu Sun +9 more
wiley +1 more source
Biliary Sterol Secretion Is Required for Functional In Vivo Reverse Cholesterol Transport in Mice [PDF]
, 2010 Niels Nijstad +4 more
openalex +1 more source
Advanced Science, EarlyView.This study develops lipid nanoparticles (LNPs) combining cationic and ionizable lipids for efficient cytosolic protein delivery. Optimized LNPs deliver functional proteins, including antibodies, enzymes, and Cas9, with high serum stability and albumin‐mediated endocytosis.
Lanfang Ren +6 more
wiley +1 more source
Peroxisome Proliferator-Activated Receptor-α Activation Promotes Macrophage Reverse Cholesterol Transport Through a Liver X Receptor–Dependent Pathway [PDF]
, 2011 Kazuhiro Nakaya +6 more
openalex +1 more source