Results 171 to 180 of about 144,135 (296)

Imatinib Promotes Reverse Cholesterol Transport and Elevates Scavenger Receptor B1

JVS - Vascular Science, 2022
Holly C. Sucharski, Emma K. Dudley, Jordan Williams, Revati Dewal, Kristin I. Stanford, Peter J. Mohler, Sara N. Koenig   +6 more
doaj   +1 more source

High density lipoprotein cholesterol: an evolving target of therapy in the management of cardiovascular disease

Vascular Health and Risk Management, 2008
Navin K Kapur, Dominique Ashen, Roger S BlumenthalDivision of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD, USAAbstract: Since the pioneering work of John Gofman in the 1950s, our understanding of high density lipoprotein ...
Navin K Kapur, Dominique Ashen, Roger S Blumenthal   +2 more
doaj  

HDL mediates reverse cholesterol transport from ram spermatozoa and induces hyperactivated motility. [PDF]

Biol Reprod, 2021
Bernecic NC, de Graaf SP, Leahy T, Gadella BM.   +3 more
europepmc   +1 more source

Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems

Advanced Science, EarlyView.
A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller, Amelie Maribel Schneider, Ellen Sjule, Renhua Sun, Xiao Han, Luca Andronico, Edward Jenkins, Michael Dustin, Adnane Achour, Erdinc Sezgin   +9 more
wiley   +1 more source

Saffron as a natural modulator of reverse cholesterol transport genes in atherosclerotic rabbits, with molecular docking insights. [PDF]

Sci Rep
Mohd Zainal Abidin Shukri Y, Abd Rahim IN, Abd Muid S, Jusoh SA, Abdul Nasir NA, Osman CP, Tahir MM, Hanafi NI, Mohd Kasim NA.   +8 more
europepmc   +1 more source

Impact of Dietary Lipids on the Reverse Cholesterol Transport: What We Learned from Animal Studies. [PDF]

Nutrients, 2021
Papotti B, Escolà-Gil JC, Julve J, Potì F, Zanotti I.   +4 more
europepmc   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

Reverse cholesterol transport: current assay methods, alterations with disease and response to therapeutic intervention. [PDF]

Front Cardiovasc Med
Playford MP, Neufeld EB, Zubirán R, Remaley AT.   +3 more
europepmc   +1 more source

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

Advanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang   +13 more
wiley   +1 more source

Retraction Note: Exogenous supplement of N-acetylneuraminic acid improves macrophage reverse cholesterol transport in Apolipoprotein E-deficient mice. [PDF]

Lipids Health Dis
Hou P, Hu S, Wang J, Yang Z, Yin J, Zhou G, Guo S.   +6 more
europepmc   +1 more source