Results 201 to 210 of about 182,598 (263)

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Dysregulated Aldosterone Production in Obesity Is Associated With Adverse Cardiac Structure, Function, and Adiposity. [PDF]

Circulation
Tsai CH, Chan JM, Milks J, Ferrebus A, Hanna I, Mahrokhian S, Newman AJ, Parisien-La Salle S, Reis Marques I, Foote K, Adler GK, Kwong RY, Jerosch-Herold M, Pitt B, Vaidya A, Brown JM.   +15 more
europepmc   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Unraveling VP2 mutations in Infectious Bursal Disease Virus (IBDV) associated with potential vaccine escape in poultry flocks in Shandong, China. [PDF]

Virol J
Liu B, Bi Y, Xie J, Su H, Ayalew LE, Luo Q, Miao L, Tang N, Kiros WA, Said A, Wang W.   +10 more
europepmc   +1 more source

Liqi Huatan Huoxue Formula Rescued Myocardial Cell Apoptosis of Coronary Microvascular Dysfunction Rat by Inhibiting Endogenous Apoptosis Pathway. [PDF]

Iran J Biotechnol
Ge Z, Ren Q, Wang X.
europepmc   +1 more source

Serological cross-reactivity and identification of an acute Seoul orthohantavirus case in a dengue outbreak from Vietnam. [PDF]

Trans R Soc Trop Med Hyg
Loc DH, Anh DD, Linh LTK, Dieu DTH, Hang NT, Lanh NH, Thom DTB, Nhung NTH, Kremsner PG, Schmidt-Chanasit J, Song LH, Toan NL, Velavan TP.   +12 more
europepmc   +1 more source

Detection and Phylogenetic Characterization of Canine Distemper Virus from a Red Fox in Hungary. [PDF]

Viruses
Szieber D, Ábrahám Á, Bányai K, Malik P, Nándori A, Fézer B, Bacsadi Á, Bodó K, Szabó A, Kemenesi G, Lanszki Z.   +10 more
europepmc   +1 more source

Qianlie Beixi Capsules Ameliorate Diabetes-Induced Erectile Dysfunction via Modulation of the HIF-1α/VEGF Signaling Pathway: Evidence From an in Vivo Study. [PDF]

Am J Mens Health
Sun L, Lin Z, Feng J, Feng W, Mao P, Yang C, Gao Z, Wang L.   +7 more
europepmc   +1 more source