Results 121 to 130 of about 50,432 (316)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Study on the reverse characteristics of Ti/6H-SiC Schottky contacts [PDF]
, 2003 The reverse I(V) measurement and analytic calculation of the electron transport across a Ti/6H-SiC Schottky barrier are presented. Based on the consideration of the barrier fluctuations and the barrier height shift caused by image charge and the applied ...
Shang YC,Chinese Acad Sci,Microelect R&D Ctr,Inst Semicond,Beijing 100083,Peoples R China. +3 more
core
Applied SciencesMultiple three-phase machine drives are inherently fault-tolerant due to their multiphase structure; however, they remain susceptible to inverter-related faults.
Živa Stare +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
The Functional and Imaging Implications of Left Bundle Branch Pacing in Ischemic Cardiomyopathy
BiomoleculesHeart failure with reduced ejection fraction due to ischemic cardiomyopathy remains a significant clinical challenge. Electrical conduction delays exacerbate symptoms by causing uncoordinated contractions, reducing pumping efficiency, and increasing ...
Fulvio Cacciapuoti +9 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
An interdigitated GaN MIS-HEMT/SBD normally-off power switching device with low ON-resistance and low reverse conduction loss [PDF]
, 2018 A three-terminal normally-off GaN switching device with highly desired low-loss reverse conduction capability was demonstrated using a chip-area-efficient device structure design.
Tang, G +8 more
core
Pressure-flowrate characteristics of electrohydrodynamic conduction pump with rod-ring electrodes including reverse flow range [PDF]
When attempting to control the heat transport by the loop heat pipe (LHP) to an extremely small amount using an electrohydrodynamic (EHD) pump, the EHD pump is exposed to conditions where the flow direction periodically changes.
Yokoyama, H. +3 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source