Results 101 to 110 of about 1,069,867 (309)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Influence of pulse and reverse current on the composition, physical-mechanical and functional properties of Ag-W coatings was studed. It's established that adding tungsten oxides to composition of silver coating, depositing with pulse and reverse ...
N. V. Bogush, A. A. Khmyl, L. K. Kushner
doaj
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
[[abstract]]This in vitro study focused on the investigation of the effect of current waveform on simultaneous glucose and lactate extraction by reverse iontophoresis. Experiments were performed using diffusion cells.
程德勝;Ching, Congo Tak-Shing;Buisson, Y;Connolly, P
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
The Willingness and its Related Factors for Reverse Mortgage in Taiwan Community
[[abstract]]The reverse mortgage has been proposed as a viable solution to be used as a supplemental financial instrument for long-term care and health care financing for those who are “house-rich but cash-poor”.
chang ling f?ng
core
Reliability of InGaN-based LEDs submitted to reverse-bias stress
This paper describes a study of the electro-optical characteristics and of the degradation of green LEDs submitted to reverse-bias stress. The results of this work indicate that: (i) under reverse-bias, the dominant conduction mechanism is tunnelling ...
ZANONI, ENRICO +13 more
core +1 more source
With the increasing integration of huge-size generators and tighter interconnection among power grids, in internal fault, the fault current of Series Compensated (SC) lines may be reversed.
Zhenxing Li +5 more
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
A yeast synthetic network for In-vivo Reverse-engineering and Modelling Assessment (IRMA)
Systems Biology approaches aim to reconstruct gene regulatory networks from experimental data. Conversely, Synthetic Biology aims at using mathematical models to design novel biological ‘circuits’ (synthetic networks) in order to seed new functions ...
Cantone, Irene
core

