Results 101 to 110 of about 1,069,867 (309)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Influence of periodic currents on the composition, physical-mechanical and functional properties of the electroplated composite Ag-W coatings

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
Influence of pulse and reverse current on the composition, physical-mechanical and functional properties of Ag-W coatings was studed. It's established that adding tungsten oxides to composition of silver coating, depositing with pulse and reverse ...
N. V. Bogush, A. A. Khmyl, L. K. Kushner
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The effect of pulsed bipolar DC current waveform on the simultaneous extraction of glucose and lactate by reverse iontophoresis

open access: yes, 2012
[[abstract]]This in vitro study focused on the investigation of the effect of current waveform on simultaneous glucose and lactate extraction by reverse iontophoresis. Experiments were performed using diffusion cells.
程德勝;Ching, Congo Tak-Shing;Buisson, Y;Connolly, P
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

The Willingness and its Related Factors for Reverse Mortgage in Taiwan Community

open access: yes, 2009
[[abstract]]The reverse mortgage has been proposed as a viable solution to be used as a supplemental financial instrument for long-term care and health care financing for those who are “house-rich but cash-poor”.
chang ling f?ng
core  

Reliability of InGaN-based LEDs submitted to reverse-bias stress

open access: yes, 2010
This paper describes a study of the electro-optical characteristics and of the degradation of green LEDs submitted to reverse-bias stress. The results of this work indicate that: (i) under reverse-bias, the dominant conduction mechanism is tunnelling ...
ZANONI, ENRICO   +13 more
core   +1 more source

The Analysis and Solution of Current Differential Protection Maloperation for Transmission Line with High Series Compensation Degree

open access: yesEnergies, 2019
With the increasing integration of huge-size generators and tighter interconnection among power grids, in internal fault, the fault current of Series Compensated (SC) lines may be reversed.
Zhenxing Li   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A yeast synthetic network for In-vivo Reverse-engineering and Modelling Assessment (IRMA)

open access: yes, 2009
Systems Biology approaches aim to reconstruct gene regulatory networks from experimental data. Conversely, Synthetic Biology aims at using mathematical models to design novel biological ‘circuits’ (synthetic networks) in order to seed new functions ...
Cantone, Irene
core  

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