Results 131 to 140 of about 1,069,867 (309)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
, 1999 Double-crystal X-ray diffraction and I-V characterization have been carried out on the GSMBE grown SiGe/Si p-n heterojunction materials. Results show that the SiGe alloys crystalline quality and the misfit dislocations are critical influences on the ...
Liu XF,Chinese Acad Sci,Inst Semicond,Mat Ctr,Beijing 100083,Peoples R China. +9 more
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Collaborative Reverse Engineering Design Experiment Using PLM Solutions [PDF]
, 2011 The current climate of economic competition forces businesses to adapt to the expectations of their customers. To achieve this, in spite of the increasing complexity of mechanical systems, it becomes necessary, amongst other things, to reduce design time.
AOUSSAT, Améziane +3 more
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, 2013 Forensic RNA analysis is gathering pace with reports of messenger RNA analysis being used in case work, and with microRNA being increasingly researched.
Uchimoto, M.L. +10 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Blue energy: electricity production from salinity gradients by reverse electrodialysis
, 2009 Energie opwekken op grote schaal uit het mengen van zoet en zout water is technisch en praktisch mogelijk. Wereldwijd is de potentie van deze schone energie – ‘blauwe stroom’ – zeer groot.
Post, J.W.
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Do non-nucleoside reverse transcriptase inhibitors contribute to lipodystrophy?
, 2005 Lipodystrophy complications, including lipoatrophy (pathological fat loss) and metabolic complications, have emerged as important long-term toxicities associated with antiretroviral therapy in the current era. The wealth of data that has accumulated over
Nolan, D.
core +1 more source
Leakage current and reverse-bias luminescence in InGaN-based light-emitting diodes
, 2009 This paper reports an electro-optical analysis of the correlation between reverse-bias leakage current and luminescence in light-emitting diodes based on InGaN. The results of the analysis suggest that i the main mechanism responsible for leakage current
G. Meneghesso +17 more
core +1 more source