Results 71 to 80 of about 2,672,892 (299)
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Review of reverse engineering systems – current state of the art
Reverse engineering (RE) has been widely applied in many segments of industry when digital or geometric models of existing physical objects are unavailable.
Zhaohui Geng, Bopaya Bidanda
doaj +1 more source
In the current inversion process of variable-polarity arc welding of aluminum alloy, drastic changes in electron and ion concentrations in arc space may lead to the failure of current commutation and arc reignition, thus affecting the arc burning ...
ZHU Zhi-ming +4 more
doaj +1 more source
Assisted reverse electrodialysis : a novel technique to decrease reverse osmosis energy demand [PDF]
Assisted reverse electrodialysis (ARED) was introduced as a pre-desalination technique for seawater reverse osmosis (RO) for drinking water production. ARED is comparable to an additional applied pressure along the osmotic pressure in pressure assisted ...
Andersen, Stephen +4 more
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Lamarck and immunity: Somatic and germline evolution of antibody genes [PDF]
Current work on the mechanism of hypermutation of somatically rearranged antibody variable (V) genes shows that the most likely mechanism involves both direct DNA modification (deamination of cytosines to uracils by AID deaminase) and strand nicking plus
Steele, E.J.
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Graphene Schottky Junction on Pillar Patterned Silicon Substrate
A graphene/silicon junction with rectifying behaviour and remarkable photo-response was fabricated by transferring a graphene monolayer on a pillar-patterned Si substrate.
Giuseppe Luongo +7 more
doaj +1 more source
Deterministic Domain Wall Motion Orthogonal To Current Flow Due To Spin Orbit Torque. [PDF]
Spin-polarized electrons can move a ferromagnetic domain wall through the transfer of spin angular momentum when current flows in a magnetic nanowire.
Bhowmik, Debanjan +7 more
core +3 more sources
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source

