Results 71 to 80 of about 1,034,106 (265)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Algorithm for Extracting Characteristic Parameters of Radiation-Voltage Conversion Devices Based on Dark Characteristic Curve

open access: yesJournal of Isotopes
Theoretical research on betavoltaic batteries require calculating characteristic parameters of the radiation-voltage conversion device,in order to predict the output characteristics under irradiation.
Jieying REN   +6 more
doaj   +1 more source

Measurement of Neutron Irradiation Effect on Reverse Current Damage Constant α for Diode [PDF]

open access: yesفصلنامه علوم و فناوری فضایی, 2013
When the electronic components are exposed to neutron irradiation, electrical properties change by interaction of neutrons in these parts such as capacitance, reverse bias current, the minority carrier lifetime, etc.
A. Hosseini   +3 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Effect of Current Type and Particle Size on Wear and Corrosion Behaviour of Electroplated Ni-B4C Composite Coatings [PDF]

open access: yesIranian Journal of Materials Science and Engineering
Ni-B4C nanocomposite coatings were deposited onto a pure Cu substrate using electroplating. Different types of current, including direct current (DC), pulse reverse current (PRC), and unipolar pulse current (PC), were applied using various concentrations
Seyed Ehsan Khadempir   +2 more
doaj  

Marine Current Energy Converters to Power a Reverse Osmosis Desalination Plant

open access: yesEnergies, 2018
Some countries are facing issues on freshwater and electricity production, which can be addressed with the use of renewable energy powered desalination systems. In the following study, a reverse osmosis desalination plant powered by marine current energy
Jennifer Leijon   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Influence of periodic currents on the composition, physical-mechanical and functional properties of the electroplated composite Ag-W coatings

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
Influence of pulse and reverse current on the composition, physical-mechanical and functional properties of Ag-W coatings was studed. It's established that adding tungsten oxides to composition of silver coating, depositing with pulse and reverse ...
N. V. Bogush, A. A. Khmyl, L. K. Kushner
doaj  

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