Results 111 to 120 of about 361,500 (307)
Reverse Engineering and Testing of Rich Internet Applications
, 2011 The World Wide Web experiences a continuous and constant evolution, where new initiatives, standards, approaches and technologies are continuously proposed for developing more effective and higher quality Web applications. To satisfy the growing request
Amalfitano, Domenico
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
A reverse crystal Engineering approach
, 2013 The enormous impact of crystal engineering in modern solid state chemistry takes advantage from the connection between a typical basic science field and the word engineering.
Macchi, Piero
core
A comparative evaluation of dynamic visualisation tools
, 2003 Despite their potential applications in software comprehension, it appears that dynamic visualisation tools are seldom used outside the research laboratory. This paper presents an empirical evaluation of five dynamic visualisation tools - AVID, Jinsight,
Wood, Murray +2 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A yeast synthetic network for In-vivo Reverse-engineering and Modelling Assessment (IRMA)
, 2009 Systems Biology approaches aim to reconstruct gene regulatory networks from experimental data. Conversely, Synthetic Biology aims at using mathematical models to design novel biological ‘circuits’ (synthetic networks) in order to seed new functions ...
Cantone, Irene
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Infusion: uma experiência de engenharia reversa orientada a objetos para sistemas legados [PDF]
, 2003 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Ciência da Computação.Este trabalho apresenta um estudo sobre métodos de engenharia reversa para Sistemas Legados.
Caldana, Cleber Gomes
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Reverse Engineering and Cognition Panglossian Memories?
Ideas y Valores, 2014 Daniel C. Dennett has dedicated a great part of his work to the conception of an application of reverse engineering and adaptationism in order to explain the evolution of the human mind.
Liliana Chaves Castaño +1 more
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