Results 131 to 140 of about 5,819,690 (295)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Ultrasonic Methods for Reverse Engineering
, 2004 A non-contact reverse engineering technique based on ultrasonic sensors for 3D surface profiling is prresented and applied to proof-of-concept samples.
TETI, ROBERTO
core
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Enriching Reverse Engineering with Feature Analysis [PDF]
, 2007 System comprehension is a prerequisite for software maintenance and evolution, but it is a time-consuming and costly activity. In an effort to support system comprehension, researchers have devised many different reverse engineering techniques.
Greevy, Orla
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
A Survey on Application of AI on Reverse Engineering for Software Analysis and Security
IEEE AccessReverse engineering process serves essential functions in software analysis and security auditing and malware detection but requires significant time and effort.
Ashutosh Ghimire +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Reverse Engineering and Cognition Panglossian Memories?
Ideas y Valores, 2014 Daniel C. Dennett has dedicated a great part of his work to the conception of an application of reverse engineering and adaptationism in order to explain the evolution of the human mind.
Liliana Chaves Castaño +1 more
doaj
Reverse Engineering Finite State Machines from Rich Internet Applications
, 2008 In the last years, Rich Internet Applications (RIAs) have emerged as a new generation of web applications offering greater usability and interactivity than traditional ones.
FASOLINO, ANNA RITA +4 more
core +1 more source