Results 121 to 130 of about 361,500 (307)

A Survey on Application of AI on Reverse Engineering for Software Analysis and Security

IEEE Access
Reverse engineering process serves essential functions in software analysis and security auditing and malware detection but requires significant time and effort.
Ashutosh Ghimire, Sahasra Rao Lingala, Junjie Zhang, Faris Alsulami, Fathi Amsaad   +4 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Node coarsening calculi for program slicing

, 2001
Several approaches to reverse and re-engineering are based upon program slicing. Unfortunately, for large systems, such as those which typically form the subject of reverse engineering activities, the space and time requirements of slicing can be a ...
M. Laurence, J. Howroyd, Fox, C, Rob Hierons, Fox, Chris, R. Hierons, S. Danicic, Laurence, MR, John Howroyd, Mark Harman, Harman, Mark, C. Fox, Sebastian Danicic, Kings College, Harman, M, Howroyd, J, Hierons, RM, Chris Fox, M. Harman, Danicic, S, Danicic, Sebastian, Laurence, Michael, Hierons, Robert, Howroyd, John   +23 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Integrated Tactile-Optical Coordinate System for the Reverse Engineering of Complex Geometry

, 2012
To meet the requirement of both high speed and high accuracy 3D measurement for reverse engineering of artefacts, an integrated contact–optical coordinate measuring system is proposed in this paper. It combines the accuracy of contact measurement using a
Longstaff, Andrew P., Myers, A., Longstaff, A. P., Li, F., Fletcher, Simon, Li, Feng, Fletcher, S., Myers, Alan   +7 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

MOODLE ARCHITECTURE THROUGH REVERSE ENGINEERING [PDF]

The Egyptian International Journal of Engineering Sciences and Technology, 2011
M Mowafy, M S Kandeel, A E Hassan
doaj   +1 more source

Reverse Engineering Finite State Machines from Rich Internet Applications

, 2008
In the last years, Rich Internet Applications (RIAs) have emerged as a new generation of web applications offering greater usability and interactivity than traditional ones.
FASOLINO, ANNA RITA, TRAMONTANA, PORFIRIO, Anna Rita Fasolino, Domenico Amalfitano, Porfirio Tramontana   +4 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source