Results 41 to 50 of about 361,500 (307)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
AnimalsPorcine parvovirus 7 (PPV7) was first discovered in swine in 2016, and PPV7 infection has been detected in aborted pig fetuses and in sows that experienced reproductive failure.
Dongliang Wang +3 more
doaj +1 more source
A Reverse Engineering Role-Play to Teach Systems Engineering Methods
Education Sciences, 2019 Students engaged in systems engineering education typically lack experience and understanding of the multidisciplinary complexity of systems engineering projects.
Alessandro Bertoni
doaj +1 more source
Filling holes in meshes using a mechanical model to simulate the curvature variation minimization [PDF]
, 2006 The presence of holes in a triangle mesh is classically ascribed to the de ciencies of the point cloud acquired from a physical object to be reverse engineered.
PERNOT, Jean-Philippe +2 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Methodology for selecting objects for reverse engineering at oil and gas industry enterprises [PDF]
E3S Web of ConferencesThe basic methods of reengineering and the possibility of their application at the enterprises of both oil and gas industry and enterprises of defense-industrial complex under the conditions of ensuring technological independence are presented.
Zhukov Aleksandr +5 more
doaj +1 more source
Engineering and reverse-engineering morality.
, 2021 Recent years have witnessed a burst of progress on building formal models of moral decision-making. In psychology, neuroscience and philosophy, the goal has been to “reverse-engineer” the principles of human morality. Meanwhile, in AI ethics, the goal has been to engineer systems that can make moral decisions, in some ways inspired by how humans do ...
Levine, Sydney +3 more
openaire +1 more source
Reverse-Engineering the Reader
Proceedings of the 2024 Conference on Empirical Methods in Natural Language ProcessingNumerous previous studies have sought to determine to what extent language models, pre-trained on natural language text, can serve as useful models of human cognition. In this paper, we are interested in the opposite question: whether we can directly optimize a language model to be a useful cognitive model by aligning it to human psychometric data.
Kiegeland, Samuel +4 more
openaire +4 more sources