Results 181 to 190 of about 278,308 (202)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

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Rotavirus reverse genetics systems: Development and application

Virus Research, 2021
Yuta Kanai, Takeshi Kobayashi
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Reverse genetics systems for SARS-CoV-2: Development and applications

Virologica Sinica, 2023
Yao-Wei Huang, Hou-Li Cai
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Development of an entirely plasmid-based reverse genetics system for 12-segmented double-stranded RNA viruses

Proceedings of the National Academy of Sciences of the United States of America, 2021
Yuta Kanai, Takeshi Kobayashi, Takahiro Kawagishi   +2 more
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SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

Cell, 2020
Scott H Randell, Alain C Borczuk
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Reverse Genetics System for a Human Group A Rotavirus.

Journal of Virology, 2020
Yuta Kanai, Takeshi Kobayashi, Takahiro Kawagishi   +2 more
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FAST Proteins: Development and Use of Reverse Genetics Systems for Reoviridae Viruses

Annual Review of Virology, 2021
Yuta Kanai, Takeshi Kobayashi
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Reverse genetics system for human rotaviruses

Microbiology and Immunology, 2020
Takayuki Murata, Satoshi Komoto, Koki Taniguchi   +2 more
exaly