Visualization of yellow fever virus infection in mice using a bioluminescent reporter virus [PDF]
Emerging Microbes and Infections, 2021 Yellow fever virus (YFV) is a re-emerging flavivirus, which can lead to severe clinical manifestations and high mortality, with no specific antiviral therapies available. The live-attenuated yellow fever vaccine 17D (YF17D) has been widely used for over eighty years.
Zhong-Yu Liu, Cheng-Feng Qin
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Rapid Construction and Characterization of Infectious cDNA Clones and Reporter Viruses of Enteroviruses, Including Enterovirus A71 and Coxsackievirus B5, with Systematic Identification of Critical Determinants for Successful Reporter Virus Generation [PDF]
VirusesEnteroviruses are positive-sense single-stranded RNA viruses and common pathogens that are responsible for diverse public health diseases. To facilitate the study of the virus biology and pathogenesis of enterovirus, we developed a rapid method for ...
Hao Zheng +6 more
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Construction of a Dengue NanoLuc Reporter Virus for In Vivo Live Imaging in Mice [PDF]
Viruses, 2022 Since the first isolation in 1943, the dengue virus (DENV) has spread throughout the world, but effective antiviral drugs or vaccines are still not available. To provide a more stable reporter DENV for vaccine development and antiviral drug screening, we
Enyue Fang +10 more
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Multi-color fluorescent reporter dengue viruses with improved stability for analysis of a multi-virus infection. [PDF]
PLoS ONE, 2018 Reporter virus is a versatile tool to visualize and to analyze virus infections. However, for flaviviruses, it is difficult to maintain the inserted reporter genes on the viral genome, limiting its use in several studies that require homogeneous virus ...
Amporn Suphatrakul +6 more
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Reporter Virus Neutralization Test Evaluation for Dengue and Zika Virus Diagnosis in Flavivirus Endemic Area [PDF]
Pathogens, 2021 Reporter virus neutralization test (RVNT) has been used as an alternative to the more laborious and time-demanding conventional PRNT assay for both DENV and ZIKV. However, few studies have investigated how these techniques would perform in epidemic areas
Jannyce G. C. Nunes +17 more
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Use of Reporter Genes in the Generation of Vaccinia Virus-Derived Vectors
Viruses, 2016 Vaccinia virus (VACV) is one of the most extensively-studied viruses of the Poxviridae family. It is easy to genetically modify, so it has become a key tool for many applications.
Sally Al Ali +3 more
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Screening and Identification of Lujo Virus Inhibitors Using a Recombinant Reporter Virus Platform [PDF]
Viruses, 2021 Christina F Spiropoulou +2 more
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Completion of the 5′ end of the porcine teschovirus genome reveals a functional S-segment and enables reverse genetics [PDF]
Journal of VirologyPorcine teschoviruses (PTVs) are swine-specific picornaviruses associated with neurological and systemic disease, ranging from severe paralytic Teschen disease to milder forms of porcine encephalomyelitis, known as Talfan disease.
Sebastian Affeldt +12 more
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Frontiers in Microbiology, 2022 The reverse genetics system is a valuable tool in the virological study of RNA viruses. With the availability of reverse genetics, the porcine reproductive and respiratory syndrome virus (PRRSV) has been utilized as a viral vector for the expression of ...
Yanhua Li +8 more
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Optimisations and Challenges Involved in the Creation of Various Bioluminescent and Fluorescent Influenza A Virus Strains for In Vitro and In Vivo Applications. [PDF]
PLoS ONE, 2015 Bioluminescent and fluorescent influenza A viruses offer new opportunities to study influenza virus replication, tropism and pathogenesis. To date, several influenza A reporter viruses have been described.
Monique I Spronken +14 more
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