Results 41 to 50 of about 174,549 (256)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

First Report of Tomato chlorosis virus in Italy

Plant Disease, 2001
During winter 2000-2001, an unusual disease of tomato was observed in some greenhouses in Sardinia, Sicily, and Apulia, in southern Italy. Plants were chlorotic and reduced in size, expanded leaves showed interveinal yellowing, and older leaves developed interveinal reddish-bronze necrosis and downward rolling.
Acotto, G P, Vaira, A M, Vecchiati M, Finetti Sialer, M M, Gallitelli D, Davino, M   +9 more
openaire   +4 more sources

Generation of a HiBiT-expressing recombinant rat hepacivirus supporting both in vivo and in vitro infection.

PLoS Pathogens
The lack of immuno-competent animal models of hepatitis C virus (HCV) infection has been an obstacle to vaccine development and research on immune responses.
Yasunori Akaike, Tomohisa Tanaka, Hirotake Kasai, Atsuya Yamashita, Yoshiharu Matsuura, Kohji Moriishi   +5 more
doaj   +1 more source

Improved protein splicing through viral passaging

mBio
Intervening proteins (inteins) are translated as subdomains within host proteins and removed through an intein-driven splicing reaction where the flanking sequences (exteins) are joined with a peptide bond.
Adam J. Hume, Dylan J. Deeney, John S. Smetana, Jacquelyn Turcinovic, John H. Connor, Marlene Belfort, Elke Mühlberger, Christopher W. Lennon   +7 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Development of a reverse genetics system for West Nile virus (Kunjin type)

Frontiers in Veterinary Science
Kunjin virus (KUNV), a naturally attenuated strain of West Nile virus (WNV), shares similar transmission modes and hosts—primarily mosquitoes, birds, and horses.
Zhen Wu, Zhen Wu, Zhen Wu, Zhen Wu, Tao Hu, Tao Hu, Tao Hu, Zhou Zhou, Zhou Zhou, Zhou Zhou, Yu He, Yu He, Yu He, Yu He, Tao Wang, Tao Wang, Tao Wang, Mingshu Wang, Mingshu Wang, Mingshu Wang, Renyong Jia, Renyong Jia, Renyong Jia, Dekang Zhu, Dekang Zhu, Dekang Zhu, Mafeng Liu, Mafeng Liu, Mafeng Liu, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Qiao Yang, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Ying Wu, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Juan Huang, Juan Huang, Juan Huang, Xumin Ou, Xumin Ou, Xumin Ou, Xumin Ou, Di Sun, Di Sun, Di Sun, Bin Tian, Bin Tian, Bin Tian, Anchun Cheng, Anchun Cheng, Anchun Cheng, Shun Chen, Shun Chen, Shun Chen, Shun Chen   +60 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

A Case Report on Chikungunya Virus-Associated Encephalomyelitis [PDF]

Case Reports in Infectious Diseases, 2018
Chikungunya is a rerising alphavirus infection that has resulted from enhanced vector competence. Alphaviruses are divided into arthritogenic viruses (old world) and encephalitogenic viruses (new world) including equine encephalitis viruses. Chikungunya is a dengue-like illness characterized by acute febrile polyarthralgia, arthritis, malaise, body ...
Harsh Khatri, Heli Shah, Dhara Roy, Kaushalendra Mani Tripathi   +3 more
openaire   +3 more sources

HIV-1 Is a Poor Inducer of Innate Immune Responses

mBio, 2019
Effective host immune responses against viral infection rely on the detection of the virus, activation of downstream signaling pathways, and the secretion of interferons (IFNs) and other cytokines.
Oya Cingöz, Stephen P. Goff
doaj   +1 more source