Results 41 to 50 of about 169,647 (254)

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

One-Step Assembly of a Porcine Epidemic Diarrhea Virus Infectious cDNA Clone by Homologous Recombination in Yeast: Rapid Manipulation of Viral Genome With CRISPR/Cas9 Gene-Editing Technology

Frontiers in Microbiology, 2022
Porcine epidemic diarrhea virus (PEDV), a swine enteric coronavirus causing acute diarrhea in piglets, is one of the major threatens to the pork industry globally.
Yanyang Zhou, Chenxi Li, Chenxi Li, Chenxi Li, Cicheng Ren, Jingbo Hu, Changxu Song, Xinjie Wang, Yanhua Li, Yanhua Li, Yanhua Li   +10 more
doaj   +1 more source

First Report of Tomato chlorosis virus in Italy

Plant Disease, 2001
During winter 2000-2001, an unusual disease of tomato was observed in some greenhouses in Sardinia, Sicily, and Apulia, in southern Italy. Plants were chlorotic and reduced in size, expanded leaves showed interveinal yellowing, and older leaves developed interveinal reddish-bronze necrosis and downward rolling.
Acotto, G P, Vaira, A M, Vecchiati M, Finetti Sialer, M M, Gallitelli D, Davino, M   +9 more
openaire   +4 more sources

Zika Virus Disease in Colombia — Preliminary Report

New England Journal of Medicine, 2020
Colombia began official surveillance for Zika virus disease (ZVD) in August 2015. In October 2015, an outbreak of ZVD was declared after laboratory-confirmed disease was identified in nine patients.Using the national population-based surveillance system, we assessed patients with clinical symptoms of ZVD from August 9, 2015, to April 2, 2016 ...
Oscar, Pacheco, Mauricio, Beltrán, Christina A, Nelson, Diana, Valencia, Natalia, Tolosa, Sherry L, Farr, Ana V, Padilla, Van T, Tong, Esther L, Cuevas, Andrés, Espinosa-Bode, Lissethe, Pardo, Angélica, Rico, Jennita, Reefhuis, Maritza, González, Marcela, Mercado, Pablo, Chaparro, Mancel, Martínez Duran, Carol Y, Rao, María M, Muñoz, Ann M, Powers, Claudia, Cuéllar, Rita, Helfand, Claudia, Huguett, Denise J, Jamieson, Margaret A, Honein, Martha L, Ospina Martínez   +25 more
openaire   +2 more sources

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

Improved protein splicing through viral passaging

mBio
Intervening proteins (inteins) are translated as subdomains within host proteins and removed through an intein-driven splicing reaction where the flanking sequences (exteins) are joined with a peptide bond.
Adam J. Hume, Dylan J. Deeney, John S. Smetana, Jacquelyn Turcinovic, John H. Connor, Marlene Belfort, Elke Mühlberger, Christopher W. Lennon   +7 more
doaj   +1 more source

VZV Replication Assays

Bio-Protocol, 2014
Varicella zoster virus (VZV) is a human herpesvirus which causes Varicella (chickenpox) upon primary infection and Zoster (shingles) following reactivation from latency (von Bokay, 1909).
Samantha Griffiths, Jürgen Haas
doaj   +1 more source

Development of a High-Throughput Serum Neutralization Test Using Recombinant Pestiviruses Possessing a Small Reporter Tag

Pathogens, 2020
A serum neutralization test (SNT) is an essential method for the serological diagnosis of pestivirus infections, including classical swine fever, because of the cross reactivity of antibodies against pestiviruses and the non-quantitative properties of ...
Madoka Tetsuo, Keita Matsuno, Tomokazu Tamura, Takasuke Fukuhara, Taksoo Kim, Masatoshi Okamatsu, Norbert Tautz, Yoshiharu Matsuura, Yoshihiro Sakoda   +8 more
doaj   +1 more source

Insertion of a GFP Reporter Gene in Influenza Virus [PDF]

Current Protocols in Microbiology, 2013
AbstractThe incorporation of a fluorescent reporter gene into a replication‐competent influenza A virus (IAV) has made it possible to trace IAV infection in vivo. This protocol describes the process of inserting a green fluorescent protein (GFP) reporter into the IAV genome using the established reverse genetics system.
Jasmine T, Perez, Adolfo, García-Sastre, Balaji, Manicassamy   +2 more
openaire   +2 more sources

Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna, Alexia Muresan, Estelle Lecluze, Karine Leduc, Nathalie Fournier, Maria Tamer, Jean‐François Delisle, Jeremi Charbonneau, Annie Viau, Jessica Darilus, Marie‐Joëlle Doré‐Bergeron, Valérie Arsenault, Evelyne Doyon‐Trottier, Stéphanie Forte, Nancy Robitaille, Yves Pastore, Thomas Pincez   +16 more
wiley   +1 more source