Results 1 to 10 of about 115,798,289 (300)

Parkinson’s disease multimodal imaging: F-DOPA PET, neuromelanin-sensitive and quantitative iron-sensitive MRI

npj Parkinson's Disease, 2021
Parkinson’s disease (PD) is a neurodegenerative synucleinopathy characterized by the degeneration of neuromelanin (NM)-containing dopaminergic neurons and deposition of iron in the substantia nigra (SN).
Frédérique Depierreux, Eric Parmentier, Laurane Mackels, Katherine Baquero, Christian Degueldre, Evelyne Balteau, Eric Salmon, Christophe Phillips, Mohamed Ali Bahri, Pierre Maquet, Gaëtan Garraux   +10 more
doaj   +1 more source

Light modulates task-dependent thalamo-cortical connectivity during an auditory attentional task

Communications Biology, 2023
Exposure to blue wavelength light stimulates alertness and performance by modulating a widespread set of task-dependent cortical and subcortical areas.
Ilenia Paparella, Islay Campbell, Roya Sharifpour, Elise Beckers, Alexandre Berger, Jose Fermin Balda Aizpurua, Ekaterina Koshmanova, Nasrin Mortazavi, Puneet Talwar, Christian Degueldre, Laurent Lamalle, Siya Sherif, Christophe Phillips, Pierre Maquet, Gilles Vandewalle   +14 more
doaj   +1 more source

Using quantitative magnetic resonance imaging to track cerebral alterations in multiple sclerosis brain: A longitudinal study

Brain and Behavior, 2023
Introduction Quantitative MRI quantifies tissue microstructural properties and supports the characterization of cerebral tissue damages. With an MPM protocol, 4 parameter maps are constructed: MTsat, PD, R1 and R2*, reflecting tissue physical properties ...
Nora Vandeleene, Camille Guillemin, Solène Dauby, Florence Requier, Maëlle Charonitis, Daphne Chylinski, Evelyne Balteau, Pierre Maquet, Emilie Lommers, Christophe Phillips   +9 more
doaj   +1 more source

Association between sleep slow-wave activity and in-vivo estimates of myelin in healthy young men

NeuroImage, 2023
Sleep has been suggested to contribute to myelinogenesis and associated structural changes in the brain. As a principal hallmark of sleep, slow-wave activity (SWA) is homeostatically regulated but also differs between individuals. Besides its homeostatic
Michele Deantoni, Marion Baillet, Gregory Hammad, Christian Berthomier, Mathilde Reyt, Mathieu Jaspar, Christelle Meyer, Maxime Van Egroo, Puneet Talwar, Eric Lambot, Sarah L. Chellappa, Christian Degueldre, André Luxen, Eric Salmon, Evelyne Balteau, Christophe Phillips, Derk-Jan Dijk, Gilles Vandewalle, Fabienne Collette, Pierre Maquet, Vincenzo Muto, Christina Schmidt   +21 more
doaj   +1 more source

Author Correction: Preserved wake-dependent cortical excitability dynamics predict cognitive fitness beyond age-related brain alterations

Communications Biology, 2021
A Correction to this paper has been published: https://doi.org/10.1038/s42003-021-01995 ...
Maxime Van Egroo, Justinas Narbutas, Daphne Chylinski, Pamela Villar González, Pouya Ghaemmaghami, Vincenzo Muto, Christina Schmidt, Giulia Gaggioni, Gabriel Besson, Xavier Pépin, Elif Tezel, Davide Marzoli, Caroline Le Goff, Etienne Cavalier, André Luxen, Eric Salmon, Pierre Maquet, Mohamed Ali Bahri, Christophe Phillips, Christine Bastin, Fabienne Collette, Gilles Vandewalle   +21 more
doaj   +1 more source

In vivo marker of brainstem myelin is associated to quantitative sleep parameters in healthy young men

Scientific Reports, 2023
The regional integrity of brain subcortical structures has been implicated in sleep–wake regulation, however, their associations with sleep parameters remain largely unexplored.
Puneet Talwar, Michele Deantoni, Maxime Van Egroo, Vincenzo Muto, Daphne Chylinski, Ekaterina Koshmanova, Mathieu Jaspar, Christelle Meyer, Christian Degueldre, Christian Berthomier, André Luxen, Eric Salmon, Fabienne Collette, D.-J. Dijk, Christina Schmidt, Christophe Phillips, Pierre Maquet, Siya Sherif, Gilles Vandewalle   +18 more
doaj   +1 more source

Light as a Modulator of Non-Image-Forming Brain Functions—Positive and Negative Impacts of Increasing Light Availability

Clocks & Sleep, 2023
Light use is rising steeply, mainly because of the advent of light-emitting diode (LED) devices. LEDs are frequently blue-enriched light sources and may have different impacts on the non-image forming (NIF) system, which is maximally sensitive to blue ...
Islay Campbell, Roya Sharifpour, Gilles Vandewalle   +2 more
doaj   +1 more source

In Vivo Imaging in Cancer [PDF]

Cold Spring Harbor Perspectives in Biology, 2010
Imaging has become an indispensable tool in the study of cancer biology and in clinical prognosis and treatment. The rapid advances in high resolution fluorescent imaging at single cell level and MR/PET/CT image registration, combined with new molecular probes of cell types and metabolic states, will allow the physical scales imaged by each to be ...
Condeelis, John, Weissleder, Ralph
openaire   +4 more sources

Fully automated 18F-fluorination of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB) for indirect labelling of nanobodies

Scientific Reports, 2022
N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB), a widely used labeling agent to introduce the 4-[18F]fluorobenzoyl-prosthetic group, is normally obtained in three consecutive steps from [18F]fluoride ion. Here, we describe an efficient one-step labeling
Surasa Nagachinta, Paolo Novelli, Yoann Joyard, Nicolas Maindron, Patrick Riss, Sylvestre Dammicco   +5 more
doaj   +1 more source

Anosognosia in Mild Cognitive Impairment: Lack of Awareness of Memory Difficulties Characterizes Prodromal Alzheimer's Disease

Frontiers in Psychiatry, 2021
While anosognosia is often present in Alzheimer's disease, the degree of awareness of cognitive difficulties in the earlier stages, such as Mild Cognitive Impairment (MCI), is less clear.
Christine Bastin, Christine Bastin, Fabrice Giacomelli, Frédéric Miévis, Christian Lemaire, Bénédicte Guillaume, Eric Salmon, Eric Salmon   +7 more
doaj   +1 more source