Results 31 to 40 of about 115,798,289 (300)
The Rise of Synaptic Density PET Imaging
Molecules, 2020 Many neurological disorders are related to synaptic loss or pathologies. Before the boom of positrons emission tomography (PET) imaging of synapses, synaptic quantification could only be achieved in vitro on brain samples after autopsy or surgical ...
Guillaume Becker +3 more
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Imaging coagulation reactions in vivo [PDF]
Thrombosis Research, 2012 Significant gaps remain in the understanding of how blood cells and the vasculature differentially support coagulation enzyme complex function leading to regulated thrombus formation in vivo. While studies employing knock-out or transgenic mice have proved useful many of these scientific gaps partly result from the lack of molecular approaches and ...
Lacramioara, Ivanciu +2 more
openaire +2 more sources
The Complex Interplay Between Trait Fatigue and Cognition in Multiple Sclerosis
Psychologica Belgica, 2022 Cognitive impairments are frequent in patients with Multiple Sclerosis (MS). Yet, the influence of MS-related symptoms on cognitive status is not clear.
C. Guillemin +5 more
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Circadian regulation of human cortical excitability
Nature Communications, 2016 Cognitive performance is impaired after prolonged wakefulness, yet the contribution of circadian rhythms for proper brain function remains unclear. Here the authors show that cortical excitability measured using TMS exhibits robust circadian dynamics ...
Julien Q. M. Ly +15 more
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On In Vivo Imaging in Cancer [PDF]
Cold Spring Harbor Perspectives in Biology, 2012 At any one moment, >500,000 proteins are present within a human cell. Imaging techniques can capture complex molecular mechanisms, including those involved in cancer, in their normal physiological context.
openaire +2 more sources
Age-related differences in the neural correlates of vivid remembering
NeuroImage, 2020 When recollecting events, older adults typically report similar memory vividness levels as young adults, while they actually retrieve fewer episodic details.
Adrien Folville +5 more
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Dosimetry for 6-[18F]Fluoro-L-DOPA in humans based on in vivo microPET scans and ex vivo tissue distribution in mice [PDF]
, 2012 Radiation dosimetry of new radiopharmaceuticals generally starts with studies in small animals such as mice and rats. The traditional technique has long been ex vivo measurement of the biodistribution over time using harvested organs at different times ...
Lemaire, Christian +8 more
core +1 more source
The pharmacokinetics of [18F]UCB-H revisited in the healthy non-human primate brain
EJNMMI Research, 2021 Background Positron Emission Tomography (PET) imaging of the Synaptic Vesicle glycoprotein (SV) 2A is a new tool to quantify synaptic density. [18F]UCB-H was one of the first promising SV2A-ligands to be labelled and used in vivo in rodent and human ...
Sébastien Goutal +11 more
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Bacteria-cancer interactions: bacteria-based cancer therapy
Experimental and Molecular Medicine, 2019 Cancer: tumor-targeting bacteria enter the anticancer arsenal Live tumor-targeting bacteria can selectively induce cancer regression and, with the help of genetic engineering, be made safe and effective vehicles for delivering drugs to tumor cells.
Mai Thi-Quynh Duong +3 more
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Looking for a balance between visual and automatic sleep scoring
npj Digital Medicine, 2023 Sleep recordings are visually classified in stages by experts in the field, based on consensus international criteria. This procedure is expensive and time-consuming.
Vincenzo Muto, Christian Berthomier
doaj +1 more source