Results 11 to 20 of about 115,798,289 (300)

Iron oxide nanoparticles and derivatives for biomedical imaging and application in cancer diagnosis and siRNA therapy [PDF]

open access: yes, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Yigit, MV   +2 more
core   +6 more sources

Genetic risk for insomnia is associated with objective sleep measures in young and healthy good sleepers

open access: yesNeurobiology of Disease, 2022
Insomnia disorder (ID) is the second most common neuropsychiatric disorder. Its socioeconomic burden is enormous while diagnosis and treatment are difficult.
Ekaterina Koshmanova   +18 more
doaj   +1 more source

Timely coupling of sleep spindles and slow waves linked to early amyloid-β burden and predicts memory decline

open access: yeseLife, 2022
Sleep alteration is a hallmark of ageing and emerges as a risk factor for Alzheimer’s disease (AD). While the fine-tuned coalescence of sleep microstructure elements may influence age-related cognitive trajectories, its association with AD processes is ...
Daphne Chylinski   +13 more
doaj   +1 more source

Positive Effect of Cognitive Reserve on Episodic Memory, Executive and Attentional Functions Taking Into Account Amyloid-Beta, Tau, and Apolipoprotein E Status

open access: yesFrontiers in Aging Neuroscience, 2021
Studies exploring the simultaneous influence of several physiological and environmental factors on domain-specific cognition in late middle-age remain scarce.
Justinas Narbutas   +22 more
doaj   +1 more source

Optimizing the Safety and Efficacy of Bio-Radiopharmaceuticals for Cancer Therapy

open access: yesPharmaceutics, 2023
The precise delivery of cytotoxic radiation to cancer cells through the combination of a specific targeting vector with a radionuclide for targeted radionuclide therapy (TRT) has proven valuable for cancer care.
Cyprine Neba Funeh   +8 more
doaj   +1 more source

The Design and Preclinical Evaluation of a Single-Label Bimodal Nanobody Tracer for Image-Guided Surgery

open access: yesBiomolecules, 2021
Intraoperative guidance using targeted fluorescent tracers can potentially provide surgeons with real-time feedback on the presence of tumor tissue in resection margins.
Pieterjan Debie   +10 more
doaj   +1 more source

Multimodality Imaging of Silica and Silicon Materials In Vivo [PDF]

open access: yes, 2018
Recent progress in the development of silica? and silicon?based multimodality imaging nanoprobes has advanced their use in image?guided drug delivery, and the development of novel systems for nanotheranostic and diagnostic applications.
Mirkka P. Sarparanta   +7 more
core   +1 more source

Application of multiline two-photon microscopy to functional in vivo imaging [PDF]

open access: yes, 2006
Kurtz R, Fricke M, Kalb J, Tinnefeld P, Sauer M. Application of multiline two-photon microscopy to functional in vivo imaging. Journal of Neuroscience Methods.
Kalb, J   +4 more
core   +1 more source

CS1-specific single-domain antibodies labeled with Actinium-225 prolong survival and increase CD8+ T cells and PD-L1 expression in Multiple Myeloma

open access: yesOncoImmunology, 2021
Multiple myeloma (MM) is a hematological malignancy characterized by the presence of clonal plasma cells in the bone marrow niche. Despite significant therapeutic advances, MM remains incurable for the majority of patients. Targeted radionuclide therapy (
Kim De Veirman   +14 more
doaj   +1 more source

In vivo imaging of apoptosis [PDF]

open access: yesCancer Biology & Therapy, 2008
Despite over a decade of intense investigation there is still no routine method for the clinical imaging of apoptosis in oncologic patients. There have been multiple tracers proposed but none as of yet has received FDA approval. Radiolabeled annexin V is one of the few radiotracers that has been widely used in Phase II trials and is still under ...
openaire   +2 more sources

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