Results 11 to 20 of about 169,647 (254)

Screening and Identification of Lujo Virus Inhibitors Using a Recombinant Reporter Virus Platform [PDF]

Viruses, 2021
Christina Spiropoulou, Michael Flint, Jessica R Spengler   +2 more
exaly   +2 more sources

Reporter Virus Neutralization Test Evaluation for Dengue and Zika Virus Diagnosis in Flavivirus Endemic Area [PDF]

Pathogens, 2021
Pei-Yong Shi, Casseb Lmn, Bruno Tardelli Diniz Nunes   +2 more
exaly   +2 more sources

Screening for anti-influenza virus compounds from traditional Mongolian medicine by GFP-based reporter virus [PDF]

Frontiers in Cellular and Infection Microbiology
Nie MS, Li XH, Zhang S, Zeng DD, Cai YR, Peng DX, Jiang T, Shi JP, Li J.   +8 more
exaly   +2 more sources

A Recombinant Porcine Reproductive and Respiratory Syndrome Virus Stably Expressing a Gaussia Luciferase for Antiviral Drug Screening Assay and Luciferase-Based Neutralization Assay

Frontiers in Microbiology, 2022
The reverse genetics system is a valuable tool in the virological study of RNA viruses. With the availability of reverse genetics, the porcine reproductive and respiratory syndrome virus (PRRSV) has been utilized as a viral vector for the expression of ...
Yanhua Li, Yanhua Li, Yanhua Li, Cicheng Ren, Chenxi Li, Chenxi Li, Chenxi Li, Yihong Xiao, Yanyang Zhou   +8 more
doaj   +1 more source

Optimisations and Challenges Involved in the Creation of Various Bioluminescent and Fluorescent Influenza A Virus Strains for In Vitro and In Vivo Applications. [PDF]

PLoS ONE, 2015
Bioluminescent and fluorescent influenza A viruses offer new opportunities to study influenza virus replication, tropism and pathogenesis. To date, several influenza A reporter viruses have been described.
Monique I Spronken, Kirsty R Short, Sander Herfst, Theo M Bestebroer, Vincent P Vaes, Barbara van der Hoeven, Abraham J Koster, Gert-Jan Kremers, Dana P Scott, Alexander P Gultyaev, Erin M Sorell, Miranda de Graaf, Montserrat Bárcena, Guus F Rimmelzwaan, Ron A Fouchier   +14 more
doaj   +1 more source

Subgenomic reporter RNA system for detection of alphavirus infection in mosquitoes. [PDF]

PLoS ONE, 2013
Current methods for detecting real-time alphavirus (Family Togaviridae) infection in mosquitoes require the use of recombinant viruses engineered to express a visibly detectable reporter protein.
J Jordan Steel, Alexander W E Franz, Irma Sanchez-Vargas, Ken E Olson, Brian J Geiss   +4 more
doaj   +1 more source

Construction and Generation of a Recombinant Senecavirus a Stably Expressing the NanoLuc Luciferase for Quantitative Antiviral Assay

Frontiers in Microbiology, 2021
Senecavirus A (SVA), also known as Seneca Valley virus, is a recently emerged picornavirus that can cause swine vesicular disease, posing a great threat to the global swine industry.
Xiaoran Guo, Kuan Zhao, Xiaona Liu, Baishi Lei, Wuchao Zhang, Xiuli Li, Wanzhe Yuan, Wanzhe Yuan, Wanzhe Yuan   +8 more
doaj   +1 more source

Identifying optimal capsid duplication length for the stability of reporter flaviviruses

Emerging Microbes and Infections, 2020
Mosquito-transmitted flaviviruses cause widespread disease across the world. To provide better molecular tools for drug screens and pathogenesis studies, we report a new approach to produce stable NanoLuc-tagged flaviviruses, including dengue virus ...
Coleman Baker, Yang Liu, Jing Zou, Antonio Muruato, Xuping Xie, Pei-Yong Shi   +5 more
doaj   +1 more source

Fitness of mCherry Reporter Tick-Borne Encephalitis Virus in Tick Experimental Models

Viruses, 2022
The tick-borne encephalitis virus (TBEV) causes a most important viral life-threatening illness transmitted by ticks. The interactions between the virus and ticks are largely unexplored, indicating a lack of experimental tools and systematic studies. One
Ádám Kevély, Veronika Prančlová, Monika Sláviková, Jan Haviernik, Václav Hönig, Eva Nováková, Martin Palus, Daniel Růžek, Boris Klempa, Juraj Koči   +9 more
doaj   +1 more source

Using recombination-dependent lethal mutations to stabilize reporter flaviviruses for rapid serodiagnosis and drug discovery

EBioMedicine, 2020
Background: Many flaviviruses are significant human pathogens that cause global public health threats. Developing research tools for studying and diagnosing these pathogens is a top priority.
Coleman Baker, Xuping Xie, Jing Zou, Antonio Muruato, Katja Fink, Pei-Yong Shi   +5 more
doaj   +1 more source