Results 51 to 60 of about 399,425 (291)
How germline genes promote malignancy in cancer cells
BioEssays, Volume 45, Issue 1, January 2023., 2023 We hypothesize that activation of a “germline program” promotes oncogenesis. Expression of otherwise germline specific genes may result in pseudomeiotic activity, thereby promoting oncogenesis through genomic instability. Other processes that are differentially regulated in the germline, such as migration and epigenetic – and metabolic plasticity, may ...
Jan Willem Bruggeman +4 more
wiley +1 more source
Primer Extension Analysis Using AMV Reverse Transcriptase
Bio-Protocol, 2012 Primer extension analysis is a useful method to determine the transcription start point or a processing site on an RNA molecule. It can also allow a quantitative measurement of an RNA species.
Harald Putzer
doaj +1 more source
AC-DC: Amplification Curve Diagnostics for Covid-19 Group Testing [PDF]
arXiv, 2020 The first part of the paper presents a review of the gold-standard testing protocol for Covid-19, real-time, reverse transcriptase PCR, and its properties and associated measurement data such as amplification curves that can guide the development of appropriate and accurate adaptive group testing protocols.
arxiv
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria
FEBS Open Bio, EarlyView.The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao +4 more
wiley +1 more source
Granular B lymphoblastic leukemia
, 2023 American Journal of Hematology, Volume 98, Issue 1, Page 210-211, January 2023.
Biswadip Hazarika, Barbara J. Bain
wiley +1 more source
FEBS Open Bio, EarlyView.Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel +3 more
wiley +1 more source
Paradigm shifts. Part II. Reverse Transcriptase. Analysis of reference stability and word frequencies [PDF]
arXiv, 2014 The reverse transcription paradigm shift in RNA tumor virus research marked by the discovery of the reverse transcriptase in 1970 was traced using co-citation and title word frequency analysis. It is shown that this event is associated with a break in citation patterns and the occurrence of previously unknown technical terms.
arxiv
A New Causal Approach to Account for Treatment Switching in Randomized Experiments under a Structural Cumulative Survival Model [PDF]
arXiv, 2021 Treatment switching in a randomized controlled trial is said to occur when a patient randomized to one treatment arm switches to another treatment arm during follow-up. This can occur at the point of disease progression, whereby patients in the control arm may be offered the experimental treatment.
arxiv
Advanced Functional Materials, EarlyView.The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai +9 more
wiley +1 more source
MicroRNA‐433‐3p enhances chemosensitivity of glioma to cisplatin by downregulating NR5A2
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 miR‐433‐3p mediated the ability of NR5A2 to regulate the malignant behavior of glioma cells Abstract Objective We attempted to investigate influence of microRNA‐433‐3p on malignant progression of glioma and identify its molecular mechanism, thus laying groundwork for glioma management.
Jun Li +9 more
wiley +1 more source