Results 91 to 100 of about 171,614 (301)

Intracellular self‐assembled nanoneedles for efficient lysosomal escape and CRISPR/Cas9 mediated gene editing

BMEMat, EarlyView.
PlaMnB was formed by cytolysin A‐tumor homing peptides (THP)‐modified bacterial membranes encapsulating the clustered regularly interspaced short palindromic repeat/CRISPR‐associated protein (CRISPR/Cas9) plasmid and manganese dioxide. THP‐containing bacterial membrane enhances PlaMnB vascular permeability and tumor targeting, and after cellular ...
Chen Zhang, Nan Zhang, Ruiqi Yang, Qian Qiu, Jiaying Huang, Jingang Liu, Silu Li, Jonathan F. Lovell, He Ren, Yumiao Zhang   +9 more
wiley   +1 more source

Parechovirus and enteroviruses among young infants with sepsis in Iran

Iranian Journal of Microbiology, 2021
Background and Objectives: Human parechoviruses (HPeV) and Human enteroviruses (EV) frequently cause a sepsis-like illness in young infants (younger than three months).
Manoochehr Makvandi, Ali Teimoori, Roya Pirmoradi, Chiman Karami, Ahmad Shamsizadeh, Abdolnabi Shabani, Kambiz Ahmadi Angali   +6 more
doaj  

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

Developmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore, Anjali Balakrishnan, Yacine Touahri, Dawn Zinyk, Humna Noman, Satoshi Okawa, Jeff Biernaskie, Carol Schuurmans   +7 more
wiley   +1 more source

Cerebrospinal fluid fistula as a complication of reverse transcriptase-polymerase chain reaction collection for the detection of coronavirus disease 2019: illustrative cases. [PDF]

J Neurosurg Case Lessons, 2023
Palavani LB, Andrade CVF, Andrade RA, Alves E, Barros MF, Barbieri JF.   +5 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Changing Epidemiology of Influenza in Post COVID-19 Era: A Retrospective Observational Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Coronavirus Disease (COVID-19) is a highly transmissible viral infection and has challenged the world’s healthcare systems. COVID-19 co-infections with other respiratory pathogens may complicate the diagnosis, treatment and ...
Milind Ramchandra Ubale, Vaibhavi Pushkar Matkari, Ayushi Pandey, Tarini V Deshmukh, Tushar R Bagle   +4 more
doaj   +1 more source

Case series - COVID-19 is unlikely to affect male fertility: Results of histopathological and reverse transcriptase polymerase chain reaction analysis. [PDF]

Can Urol Assoc J, 2022
Masterson JM, Bui C, Hasan W, Zhang Y, Huynh C, Jawanda H, Luthringer D, Tourtellotte W, Vail E, Garcia MM.   +9 more
europepmc   +1 more source

Rapid Detection of Highly Pathogenic Avian Influenza H5N1 Virus by TaqMan Reverse Transcriptase-Polymerase Chain Reaction [PDF]

, 2009
B.P. Shankar, R. N. S. Gowda, Bramhadev Pattnaik, B. Manjunath, S. S. Patil, H.K. Pradhan   +5 more
openalex   +1 more source

Mutation type‐specific transcriptomic signatures and readthrough therapy rescue in SMC1A‐related developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to investigate the molecular consequences of pathogenic variants in the SMC1A gene—particularly those associated with developmental and epileptic encephalopathy (DEE85)—and to evaluate the therapeutic potential of ataluren in restoring SMC1A function and mitigating disease‐related transcriptomic and genomic ...
Maddalena Di Nardo, Francesca Sardina, Maria M. Pallotta, Iñigo Marcos‐Alcalde, Paulino Gómez‐Puertas, Cinzia Rinaldo, Ian D. Krantz, Antonio Musio   +7 more
wiley   +1 more source

Comparison of Commercially Available Thermostable DNA Polymerases with Reverse Transcriptase Activity in Coupled Reverse Transcription Polymerase Chain Reaction Assays

Methods and Protocols
Reverse transcription polymerase chain reaction (RT-PCR) is an important tool for the detection of target RNA molecules and the assay of RNA pathogens.
Evgeniya V. Smirnova, Konstantin A. Blagodatskikh, Ekaterina V. Barsova, Dmitriy A. Varlamov, Vladimir M. Kramarov, Konstantin B. Ignatov   +5 more
doaj   +1 more source