Results 91 to 100 of about 265,335 (347)

The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients [PDF]

open access: yes, 2001
Background and Objectives. Detection of PML-RAR alpha transcripts by RT-PCR is now established as a rapid and sensitive method for diagnosis of acute promyelocytic leukemia (APL), Although the majority of patients in longterm clinical remission are ...
Carrara, P   +11 more
core  

t(X;18) Reverse Transcriptase-Polymerase Chain Reaction Demonstrating a Variant Transcript [PDF]

open access: yesThe Journal of Molecular Diagnostics, 2002
Maureen J. O’Sullivan’s current address is the Department of Pathology, Edinburgh University Medical School, Edinburgh, Scotland.
John D. Pfeifer   +3 more
openaire   +3 more sources

Molecular characterization, cloning and sequencing of coat protein gene of a Pakistani potato leaf roll virus isolate and its phylogenetic analysis [PDF]

open access: yes, 2016
Total RNA was extracted from potato leaf roll virus (PLRV) positive potato plants and complementary DNA were synthesized. Reverse transcriptase polymerase chain reaction (RT-PCR) based detection conditions were optimized by using coat protein (CP) gene ...
Hossain, Md Belal   +3 more
core   +2 more sources

Intestinal Epithelial‐Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78‐mediated Endoplasmic Reticulum Stress

open access: yesAdvanced Science, EarlyView.
USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian   +9 more
wiley   +1 more source

Possible Central Nervous System Infection by SARS Coronavirus

open access: yesEmerging Infectious Diseases, 2004
On day 22 of illness, generalized tonic-clonic convulsion developed in a 32-year-old woman with severe acute respiratory syndrome (SARS). Cerebrospinal fluid tested positive for SARS coronavirus (SARS-CoV) by reverse transcriptase–polymerase chain ...
Kwok-Kwong Lau   +5 more
doaj   +1 more source

Combining mammaglobin and carcinoembryonic mRNA markers for early detection of micrometastases from breast cancers - a molecular study of 59 patients [PDF]

open access: yes, 2006
Introduction: As many as 30% of node-negative breast cancer patients relapse within five years, suggesting that current histological detection methods are inadequate for identifying metastatic disease. Detecting small number of cancer cells in the breast
Dastan, J.   +8 more
core  

Glucose‐Responsive PAGR1‐Regulated Skeletal Muscle Gene Program Controls Systemic Glucose Homeostasis and Hepatic Metabolism

open access: yesAdvanced Science, EarlyView.
The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding   +19 more
wiley   +1 more source

SARS-CoV-2 RNA detection in cerebrospinal fluid: Presentation of two cases and review of literature

open access: yesBrain, Behavior, & Immunity - Health, 2021
Neurological manifestations of SARS-CoV-2 infection are multiple and heterogeneous. However, confirmation of nervous system impairment by viral RNA detection in cerebrospinal fluid (CSF) is uncommon.
María Belén Luis   +3 more
doaj  

Norwalk-Like Viral Gastroenteritis Outbreak in U.S. Army Trainees

open access: yesEmerging Infectious Diseases, 2000
An outbreak of acute gastroenteritis hospitalized 99 (12%) of 835 U.S. Army trainees at Fort Bliss, El Paso, Texas, rom August 27 to September 1, 1998.
Mark K. Arness   +13 more
doaj   +1 more source

Respiratory syncytial virus outbreak in a long-term care facility detected using reverse transcriptase polymerase chain reaction: an argument for real-time detection methods. [PDF]

open access: yes, 2009
ObjectivesTo report an outbreak of respiratory synctyial virus (RSV) in a long-term care facility (LTCF) during ongoing routine respiratory illness surveillance.DesignRapid antigen testing, viral culture, direct fluorescent antibody (DFA) testing, and ...
Caram, L Brett   +9 more
core  

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