Results 151 to 160 of about 273,066 (341)

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

Cost analysis of coronavirus disease 2019 test strategies using pooled reverse transcriptase-polymerase chain reaction technique. [PDF]

J Clin Lab Anal, 2022
Kim EY, Kim J, Sung H, Jo MW.
europepmc   +1 more source

Typing of field isolates of Infectious bronchitis virus from Kerala using reverse transcriptase polymerase chain reaction-restriction fragment length polymorphism analysis

, 2022
C.B. Sruthy, Surya Sankar, M. Mini, P.M. Priya, K.B. Dhanush   +4 more
openalex   +1 more source

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

Developmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore, Anjali Balakrishnan, Yacine Touahri, Dawn Zinyk, Humna Noman, Satoshi Okawa, Jeff Biernaskie, Carol Schuurmans   +7 more
wiley   +1 more source

Effectiveness and use of reverse transcriptase polymerase chain reaction point of care testing in a large-scale COVID-19 surveillance system. [PDF]

Pharmacoepidemiol Drug Saf, 2022
Mack CD, Wasserman EB, Hostler CJ, Solomon G, Anderson DJ, Walton P, Hawaldar K, Myers E, Best M, Eichner D, Mayer T, Sills A.   +11 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

The Expression of hTERT mRNA and p16 Protein in Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2009
Background and objective hTERT and p16 are involved in oncogenesis and development of tumor. The aim of this study is to investigate the expression of human telomerase reverse transcriptase (hTERT) and p16 in non-small cell lung cancer (NSCLC).
Lei XIAN, Huafu ZHOU, Xinghua ZHANG, Bangde XUE, Jianji GUO, Xu FENG   +5 more
doaj  

Human Lysozyme Transgenic Maize Improves Colonic Inflammation by Inhibiting the cGAS/STING Signaling Pathway in DSS‐Induced Colitis Mice

Food Frontiers, EarlyView.
Human lysozyme (HLZ) possesses the function of ameliorating intestinal inflammation. HLZ transgenic maize restored intestinal barrier function in colitis mice. HLZ‐feed inhibited the cGAS/STING signaling pathway by ameliorating DSS‐induced mitochondrial dysfunction.
Yinuo Yu, Yaqin Li, Xuan Chen, Rentao Song, Zhenyi Qiao, Weiwei Qi   +5 more
wiley   +1 more source

Rare Structural Variants Uncovered by Optical Genome Mapping in Multisystem Inflammatory Syndrome in Children (MIS‐C)

Advanced Genetics, EarlyView.
This study applies optical genome mapping (OGM) to children with multisystem inflammatory syndrome (MIS‐C), revealing rare structural and copy number variants in and near immune‐related genes, including ORAI1, STAT4, ITPR1, BATF, CFHR5, and DOCK2.
Catherine A. Brownstein, Caspar I. van der Made, Kristin Cabral, Shira Rockowitz, Donghun Kang, Maximilian Schieck, Andy Wing Chun Pang, Jeffrey M. Robinson, Alex R. Hastie, Alka Chaubey, The C.O.V.I.D19hostgenomeS.V. Consortium, Alexander Hoischen, Alan H. Beggs, Clement A. Adebamowo, Ali Andalibi, Silviu‐Alin Bacanu, Vineet Bafna, Justin Bahl, Hayk Barseghyan, Alan Beggs, Laurie Burdette, Manish Butte, Pantelis Constantoulakis, Keith A. Crandall, Siavash R. Dehkordi, Megan Dennis, Gang Fang, Olivier Fedrigo, Darren Finlay, Michael A. Goldman, Umamaheswaran Gurusamy, Vanessa Hayes, Glenn Hickey, Alexander Hoischen, Thomas Illig, Alexander Ioannidis, Erich Jarvis, Naoru Koizumi, Ravindra Kolhe, Meriem Laamarti, Celia Labranche, Sandra Leibel, Brynn Levy, Matthew Loose, Claudio Mello, Jamal Nasir, Thuy L. Phung, Chethan P. Venkatasubba Rao, Ted Ross, Nikhil S. Sahajpal, Rashmi K. Shamanna, Daniela C. Soto, Amir Trablesi, Zi‐Xuan Wang, Sion Llewelyn Williams, Victoria Wright, Hua Zhao, Michael Zody   +57 more
wiley   +1 more source

Development of a Multiplex TaqMan Assay for Rapid Detection of Groundnut Bud Necrosis Virus: A Quarantine Pathogen in the USA

Viruses
Groundnut bud necrosis orthotospovirus (GBNV), a tripartite single-stranded RNA virus, poses a significant threat to United States agriculture. GBNV is a quarantine pathogen, and its introduction could lead to severe damage to economically important ...
Anushi Suwaneththiya Deraniyagala, Avijit Roy, Shyam Tallury, Hari Kishan Sudini, Albert K. Culbreath, Sudeep Bag   +5 more
doaj   +1 more source