Results 331 to 340 of about 515,505 (407)

Modulation of podocyte extracellular matrix remodeling in membranous nephropathy by the NFATc3/LRRC55/BK channel pathway

open access: yesJournal of Cell Communication and Signaling, Volume 19, Issue 2, June 2025.
Molecular Mechanism of NFATc3/LRRC55‐Mediated ECM Remodeling via the BK Ion Channel in Aggravating ANG II‐Induced Podocyte Injury in MN. Abstract Membranous nephropathy (MN) is a common glomerular disease characterized by podocyte injury. Although previous studies highlighted the leucine‐rich repeat‐containing 55/big potassium (LRRC55/BK) channel axis ...
Yaling Guo   +5 more
wiley   +1 more source

Spatiotemporal distribution of neural crest cells in the common wall lizard Podarcis muralis

open access: yesDevelopmental Dynamics, Volume 254, Issue 6, Page 551-567, June 2025.
Abstract Background Neural crest cells (NCCs) are migratory embryonic stem cells that give rise to a diverse set of cell types. Here we describe the dynamic distribution of NCCs in developing embryos of the common wall lizard Podarcis muralis inferred from 10 markers.
Robin Pranter, Nathalie Feiner
wiley   +1 more source

Calpain inhibition in a transgenic model of calpastatin overexpression facilitates reversal of myocardial hypertrophy

open access: yesESC Heart Failure, Volume 12, Issue 3, Page 2256-2266, June 2025.
Abstract Aims It was recently demonstrated that the intracellular signalling phosphatase calcineurin is subject to cleavage by the protease calpain, resulting in a truncated calcineurin fragment that is a strong inductor of myocardial hypertrophy. We now address the question of whether inhibition of calpain function in cardiomyocytes, and thereby ...
Gregor Sachse   +9 more
wiley   +1 more source

The Protective Effects of Lactobacillus reuteri Combined With Clostridium butyricum Miyairi 588 on Intestinal Barrier Function, Water Transport, and Oxidative Stress in a Rat Model of 5FU‐Induced Diarrhea

open access: yesFood Science &Nutrition, Volume 13, Issue 6, June 2025.
I recommend using Figure Graphical abstracts for the graphical table of contents and publication cover. This figure effectively illustrates probiotics LCs have therapeutic effects in a rat model of 5FU‐induced diarrhea, making it a compelling visual summary of our research.
Sheau‐Chung Tang   +7 more
wiley   +1 more source

Cornus officinalis Extract Ameliorates Fructose‐Induced Hepatic Steatosis in Mice by Sustaining the Homeostasis of Intestinal Microecology and Lipid Metabolism

open access: yesFood Science &Nutrition, Volume 13, Issue 6, June 2025.
Our study demonstrates that Cornus officinalis ethanol extract delays the progression of fructose‐driven NAFLD by suppressing lipid metabolic dysfunction and gut microbiota‐mediated liver inflammation. Our study provides a novel potential strategy that dietary supplementation with C.
Liang Chen   +9 more
wiley   +1 more source

Abstracts

open access: yesMolecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Single‐microbe RNA sequencing uncovers unexplored specialized metabolic functions of keystone species in the human gut

open access: yesiMeta, Volume 4, Issue 3, June 2025.
The human body is inhabited by trillions of microorganisms that play a crucial role in health and diseases. Although our understanding of the species and functional composition of the human gut microbiome is rapidly expanding, species–function heterogeneity and dynamic activities in human microecosystem niches remain unclear.
Yifei Shen   +21 more
wiley   +1 more source

Purinergic Receptor P2Y2 Activity Prevents DNA Damage in CCl4‐Induced Hepatic Fibrosis

open access: yesJournal of Cellular Biochemistry, Volume 126, Issue 6, June 2025.
ABSTRACT DNA damage is one of the key processes that underlie hepatic fibrosis, and its progression could lead to the development of neoplastic events and ultimately hepatocarcinoma. Tissue injury, including DNA damage, can involve the activation of purinergic signaling.
Erandi Velázquez‐Miranda   +8 more
wiley   +1 more source

The Clinical and Metabolic Profiles in Menstrual Changes Among Reproductive‐Aged Women Post‐COVID‐19

open access: yesMedComm, Volume 6, Issue 6, June 2025.
This study recruited 253 Chinese women of reproductive age and post‐COVID‐19 infection. Serious factors, including age and perceived stress, contribute to menstrual changes while general medical condition was the only independent risk factor. Notable metabolic change existed in group with any menstruation changes, with special sex hormone: T decreased ...
Wei Wang   +13 more
wiley   +1 more source

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