Results 81 to 90 of about 275,235 (344)

Semiquantification of circulating hepatocellular carcinoma cells by reverse transcriptase polymerase chain reaction [PDF]

British Journal of Cancer, 1997
Hepatocellular carcinoma (HCC) is one of the most common and rapidly fatal malignancies worldwide. Treatment options are severely limited by the frequent presence of metastases. If hepatocyte-specific mRNAs are detected in the circulation, it is possible to infer the presence of circulating, presumably malignant, liver cells. If these can be quantified,
I H, Wong, T, Leung, S, Ho, W Y, Lau, M, Chan, P J, Johnson   +5 more
openaire   +2 more sources

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

Quadruple-negative RT-PCR assay for COVID-19, but clinically and radiologically COVID pneumonia with POTS: Case report and case-based review

SAGE Open Medical Case Reports, 2021
A 25-year-old woman with a background history of bronchial asthma and intellectual disability presented to hospital with progressively worsening dyspnoea.
Nithya Rajendran, Puteri Maisarah Rameli, Grace Collins   +2 more
doaj   +1 more source

From traumatic childhood to cocaine abuse: the critical function of the immune system [PDF]

, 2018
Background: Experiencing traumatic childhood is a risk factor for developing substance use disorder (SUD), but the mechanisms that underlie this relationship have not been determined.
Aricò, Eleonora, Bussone, Silvia, Carola, Valeria, Casella, Pietro, Catale, Clarissa, Chiurchiù, Valerio, Di Sabato, Paola, D’Argenio, Alberto, Guatteo, Ezia, Lo Iacono, Luisa, Maccarrone, Mauro, Martini, Alessandro, Mercuri, Nicola B., Perrone, Fabiana, Puglisi-Allegra, Stefano, Troisi, Alfonso, Valzania, Alessandro, Viscomi, Maria Teresa   +17 more
core   +1 more source

t(X;18) Reverse Transcriptase-Polymerase Chain Reaction Demonstrating a Variant Transcript [PDF]

The Journal of Molecular Diagnostics, 2002
Maureen J. O’Sullivan’s current address is the Department of Pathology, Edinburgh University Medical School, Edinburgh, Scotland.
Maureen J, O'Sullivan, Peter A, Humphrey, Louis P, Dehner, John D, Pfeifer   +3 more
openaire   +2 more sources

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

West Nile Virus Detection in Urine

Emerging Infectious Diseases, 2005
We report West Nile virus (WNV) RNA in urine collected from a patient with encephalitis 8 days after symptom onset. Viral RNA was detected by reverse transcriptase–polymerase chain reaction (RT-PCR).
Jessica H. Tonry, Craig B. Brown, Cecil B. Cropp, Juliene K.G. Co, Shannon N. Bennett, Vivek R. Nerurkar, Timothy Kuberski, Duane J. Gubler   +7 more
doaj   +1 more source

Investigation into the relationship between ethylene and sulfur assimilation in Arabidopsis thaliana and onion (Allium cepa L.) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science (with Honours) in Biochemistry at Massey University [PDF]

, 2006
The phytohormone ethylene (C2H4) mediates the adaptive responses of plants to various nutrient deficiencies including iron (Fe)-deficiency, phosphorus (P)-deficiency and potassium (K)-deficiency.
Sanggang, Fiona Ann
core  

Genetic diversity of Brazilian isolates of feline immunodeficiency virus [PDF]

, 2010
We isolated Feline immunodeficiency virus (FIV) from three adult domestic cats, originating from two open shelters in Brazil. Viruses were isolated from PBMC following co-cultivation with the feline T-lymphoblastoid cell line MYA-1.
A Duarte, A Reche Jr, AN Martins, B. J. Willett, BJ Willett, BJ Willett, BM Teixeira, Bruno Marques Teixeira, C Palmer, DL Lerner, DL Sodora, EA Weaver, EJ Verschoor, F Reggeti, FA Caxito, G Pancino, G Ryan, GA Dean, J. C. M. Cruz, J. K. P. Reis, JH Elder, JJ Hayward, JK Yamamoto, KH Siebelink, L. J. Richtzenhain, M Goodenow, M Torten, M. J. Hosie, M. K. Hagiwara, MA Rigby, MJ Hosie, MJ Hosie, MJ Hosie, MR Pecoraro, MT Kyaw-Tanner, MW Cho, N. Logan, NC Pedersen, P. E. Brandão, R Kann, RA Olmsted, RL Talbott, RV English, S Kakinuma, S Lombardi, T Hohdatsu, T Hohdatsu, T Miyazawa, TA Hall, W Huisman, WK Greene   +50 more
core   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source