Results 81 to 90 of about 558,507 (269)

Silica nanoparticles induce reversible damage of spermatogenic cells via RIPK1 signal pathways in C57 mice

open access: yesInternational Journal of Nanomedicine, 2016
Lihua Ren,1,2 Jin Zhang,1,2 Yang Zou,1,2 Lianshuang Zhang,1,2 Jialiu Wei,1,2 Zhixiong Shi,1,2 Yanbo Li,1,2 Caixia Guo,2 Zhiwei Sun,1,2 Xianqing Zhou1,21Department of Toxicology and Hygienic Chemistry, School of Public Health, 2Beijing Key Laboratory of ...
Ren L   +9 more
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Cystic lung disease in tuberculosis: An unusual presentation

open access: yesLung India, 2013
Cysts in the lung can arise due to large number of causes out of which tuberculosis is very rare, We report a case of tuberculosis in a young female presenting as a febrile illness and respiratory failure with radiological features of cystic lung disease.
Animesh Ray   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Organic room temperature phosphorescence co‐crystal with reversible acid/base stimulus response

open access: yesSmart Molecules
Stimulus‐responsive organic room temperature phosphorescent (RTP) materials have received significant attention in bioimaging, sensing, and data storage because of their controllable dynamic variability and rapid response.
Chenchen Zhang   +5 more
doaj   +1 more source

Reversible Computation and Reversible Programming Languages

open access: yesElectronic Notes in Theoretical Computer Science, 2010
AbstractA reversible programming language supports deterministic forward and backward computation. This tutorial focuses on a high-level reversible programming language Janus. In common with other programming paradigms, reversible programming has its own programming methodology. Janus is simple, yet powerful, and its constructs can serve as a model for
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

On the Construction of Reversible Automata for Reversible Languages [PDF]

open access: yes, 2002
Reversible languages occur in many different domains. Although the decision for the membership of reversible languages was solved in 1992 by Pin, an effective construction of a reversible automaton for a reversible language was still unknown. We give in this paper a method to compute a reversible automaton from the minimal automaton of a reversible ...
openaire   +1 more source

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