Results 81 to 90 of about 840,630 (239)

Recent advancements in smart responsive tissue adhesives for medical applications

open access: yesFrontiers in Medicine
Bioadhesives have emerged as a promising alternative to conventional sutures, offering rapid and robust tissue integration while overcoming limitations such as time-consuming procedures and risks of secondary tissue damage.
Shiqi Lin   +5 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Proyecto de factibilidad destinada a la fabricación y comercialización de línea de ropa reversible juvenil en la ciudad de Guayaquil [PDF]

open access: yes, 2011
El estudio que se presenta a continuación nos indica la factibilidad para la fabricación y comercialización de ropa reversible en la ciudad de Guayaquil, lugar en que actualmente ninguna empresa se ha destacado en la producción de este tipo de prendas,
Solano Sesme, Shirley Stefania   +2 more
core  

Reversible reactions

open access: yes, 2016
Permite investigar o desenvolvimento de uma reação química reversível e como a energia total afeta a taxa de reação e temperaturaComponente Curricular::Ensino Médio ...
Barbera, Jack   +2 more
core   +2 more sources

Docosahexanoic acid (DHA) reduces brain damage induced by reversible middle cerebral artery occlusion (MCAO) in mice

open access: yesZagazig Journal of Pharmaceutical Sciences, 2013
Stroke is a leading cause of death and permanent disability in adults worldwide. The only FDA-approved treatment for acute ischemic stroke is the intravenous recombinant tissue plasminogen activator (rt-PA) within 3 hours of onset Among the mechanisms ...
Waleed Barakat   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Drug-tolerant persister cells: the deadly survivors in hematological malignancies

open access: yesFrontiers in Pharmacology
Although the prognosis of patients with hematologic cancers has improved significantly owing to the advance of radiotherapy, chemotherapy, targeted therapies, immunotherapies, and hematopoietic stem cell transplantation therapy, disease relapse and ...
Qianying Ma   +8 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Toward an Energy Efficient Language and Compiler for (Partially) Reversible Algorithms

open access: yes, 2016
We introduce a new programming language for expressing reversibility, Energy-Efficient Language (Eel), geared toward algorithm design and implementation.
Tyagi, Nirvan   +5 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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