Results 61 to 70 of about 795,603 (249)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

An approach for automated generation of quantum computing models using deep learning

open access: yesAin Shams Engineering Journal
Quantum computing promises remarkable computational power with minimal energy consumption. However, the complexity of developing quantum circuits and codes hinders fully exploiting this potential.
Niyazi Furkan Bar, Mehmet Karakose
doaj   +1 more source

Stabilizer Codes and Quantum Error Correction [PDF]

open access: yes, 1997
Controlling operational errors and decoherence is one of the major challenges facing the field of quantum computation and other attempts to create specified many-particle entangled states.
Daniel Gottesman, Gottesman, Daniel Eric
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

A Turbo-Detection Aided Serially Concatenated MPEG-4/TCM Videophone Transceiver

open access: yes, 2004
A Turbo-detection aided serially concatenated inner Trellis Coded Modulation (TCM) scheme is combined with four different outer codes, namely with a Reversible Variable Length Code (RVLC), a Non-Systematic Convolutional (NSC) code a Recursive Systematic ...
Ng, S. X.   +3 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Reversible Multiple Items Authentication Scheme for WSNs

open access: yesIEEE Access, 2020
In this article, a reversible authentication scheme for wireless sensor networks (WSNs) is proposed aimed at multiple items authentication and good imperception of transmitted data. Firstly, the WSNs data stream is divided into some authentication groups,
Guangyong Gao   +5 more
doaj   +1 more source

Design of LDPC Codes: A Survey and New Results [PDF]

open access: yes, 2006
This survey paper provides fundamentals in the design of LDPC codes. To provide a target for the code designer, we first summarize the EXIT chart technique for determining (near-)optimal degree distributions for LDPC code ensembles.
Ryan, William E.   +11 more
core   +1 more source

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