Results 71 to 80 of about 94,375 (298)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Anwendung des ETCS-Mode Reversing in Eisenbahntunnel
Diese Diplomarbeit untersucht die technischen und betrieblichen Möglichkeiten des ETCS-Mode Reversing. Dies erfolgt vergleichend mit bisherigen Methoden zum Rückwärtsfahren von Zügen im Brandfall und dem Fall einer betrieblichen Stö-rung.
Rothbarth, Tim
core +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Effects of current density on Zn reversibility
Chemical ScienceThis perspective provides a comprehensive examination of the rate-dependent stability of Zn anodes by comparing and contrasting various nucleation-growth theories and models relevant to current density.
Licheng Miao, Wenqi Jia, Lifang Jiao
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Documenting Unserdeutsch: Reversing colonial amnesia
, 2017 Unserdeutsch, also known as Rabaul Creole German, is the only known German-lexifier creole. This critically endangered language has its origins in an orphanage in German New Guinea for mixed-race children, where Standard German was taught by mission ...
Volker, Craig A. +4 more
core +1 more source
, 2020 Formation of the honeycomb-like electrodes of copper by the regime of reversing current (RC) in the second range has been investigated. Morphological and structural characteristics of this electrode type obtained by various parameters of RC regimes ...
Živković, Predrag M. +4 more
core +1 more source