Results 91 to 100 of about 2,417,430 (400)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Loneliness: A Concept Analysis [PDF]

open access: yes, 2008
TOPIC. Loneliness is a universal human experience recognized since the dawn of time, yet it is unique for every individual. Loneliness can lead to both depression and low self‐esteem. PURPOSE. This article explicates the concept of loneliness through the
Bekhet, Abir K.   +1 more
core   +1 more source

Exploring the connection between relational capital and female entrepreneurs [PDF]

open access: yes, 2017
.Among intangible assets of contemporary companies, relational capital (RC) is a relevant strategic asset as well as a dimension of intellectual capital.
Lombardi, Rosa, Paoloni, Paola
core   +1 more source

Industry 4.0 in Management Studies: A Systematic Literature Review

open access: yesSustainability, 2018
Recent developments in production processes and their automation have led to the definition of the Fourth Industrial Revolution, commonly known as “Industry 4.0”.
Michela Piccarozzi   +2 more
semanticscholar   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

A methodology for analysing and evaluating narratives in annual reports: a comprehensive descriptive profile and metrics for disclosure quality attributes [PDF]

open access: yes, 2004
There is a consensus that the business reporting model needs to expand to serve the changing information needs of the market and provide the information required for enhanced corporate transparency and accountability. Worldwide, regulators view narrative
Beattie, V., Fearnley, S., McInnes, W.
core   +1 more source

Factors influencing pharmaceutical pricing - a scoping review of academic literature in health science

open access: yesJournal of Pharmaceutical Policy and Practice, 2019
Introduction Pharmaceutical pricing has only recently gained space in mainstream health science literature. Objectives Bibliometric and content description of health science academic literature and ad hoc analysis of grey literature on factors ...
Maria Angelica Borges dos Santos   +4 more
doaj   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

A Systematic Literature Review on English and Bangla Topic Modeling [PDF]

open access: hybrid, 2021
Md. Basim Uddin Ahmed   +3 more
openalex   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

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