Results 101 to 110 of about 2,658,581 (378)
Knowledge Mapping for Open Sensemaking Communities [PDF]
, 2007 By analogy to cartographic representations of spatial worlds, Knowledge Maps provide an ‘aerial view’ of a topic by highlighting key elements and connections.
Buckingham Shum, Simon, Okada, Alexandra
core +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
International Brazilian Journal of Urology, 2012 Objective To perform a systematic review and meta-analysis of all randomized controlled trials comparing the efficacy of Sipuleucel-T versus placebo for asymptomatic or minimally symptomatic metastatic castration-refractory prostate cancer (mCRPC).
Tobias Engel Ayer Botrel +6 more
doaj +1 more source
Determinants and outcomes of motivation in health professions education: a systematic review based on self-determination theory [PDF]
Journal of Educational Evaluation for Health Professions, 2016 Purpose: This study aimed at conducting a systematic review in health professions education of determinants, mediators and outcomes of students’ motivation to engage in academic activities based on the self-determination theory’s perspective.
Cesar Orsini +2 more
doaj +1 more source
The Impact of Parental Divorce on the Intimate Relationships of Adult Offspring: A Review of the Literature [PDF]
, 2010 This literature review provides a comprehensive overview on the impact of parental divorce on the intimate relationships of adult offspring. In this review, the effects of parental divorce on adults’ relationships are associated with factors, as outlined
Ottaway, Amber
core +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
BMC Medical Research MethodologyObjective To develop and compare the accuracy of different PubMed search strategies (filters) for systematic and non-systematic reviews in dental journals. Methods This validation study included articles published in 2019 in 15 dental journals.
Victor Nascimento Fontanive +4 more
doaj +1 more source
Kidney collecting system anatomy applied to endourology - a narrative review
International Brazilian Journal of UrologyObjective: To evaluate the surgical anatomy of the kidney collecting system through a narrative review of the literature, highlighting its importance during diagnosis and its approach during surgical procedures for the treatment of renal stones ...
Ana Raquel M. Morais +2 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source