Results 121 to 130 of about 2,417,430 (400)

Stability and aggregation of ranked gene lists [PDF]

, 2009
Ranked gene lists are highly instable in the sense that similar measures of differential gene expression may yield very different rankings, and that a small change of the data set usually affects the obtained gene list considerably.
A.-L. Boulesteix, Aerts, Baldi, Boulesteix, Breitling, Eden, Fox, Gabrielsson, Ioannidis, Irizarry, Jeffery, Jha, Kooperberg, Kutalik, Lin, M. Slawski, Ma, Mukherjee, Pavlidis, Qiu, Stolovitzky, Strimmer, Strobl, Xu, Yang, Zintzaras   +25 more
core   +1 more source

Kidney collecting system anatomy applied to endourology - a narrative review

International Brazilian Journal of Urology
Objective: To evaluate the surgical anatomy of the kidney collecting system through a narrative review of the literature, highlighting its importance during diagnosis and its approach during surgical procedures for the treatment of renal stones ...
Ana Raquel M. Morais, Luciano A. Favorito, Francisco J. B. Sampaio   +2 more
doaj   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Knowledge Mapping for Open Sensemaking Communities [PDF]

, 2007
By analogy to cartographic representations of spatial worlds, Knowledge Maps provide an ‘aerial view’ of a topic by highlighting key elements and connections.
Buckingham Shum, Simon, Okada, Alexandra
core   +1 more source

Consumer preferences for electric vehicles: a literature review

, 2017
Widespread adoption of electric vehicles (EVs) may contribute to the alleviation of problems such as environmental pollution, global warming and oil dependency.
F. Liao, E. Molin, B. van Wee
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Welcoming the new, revisiting the old: a brief glance at cytopathology reporting systems for lung, pancreas, and thyroid [PDF]

Journal of Pathology and Translational Medicine
This review addresses new reporting systems for lung and pancreatobiliary cytopathology as well as the most recent edition of The Bethesda Reporting System for Thyroid Cytopathology.
Rita Luis, Balamurugan Thirunavukkarasu, Deepali Jain, Sule Canberk   +3 more
doaj   +1 more source

A Review of the Empirical Literature on Meaningful Work: Progress and Research Agenda

Human Resource Development Review, 2018
Meaningful work is a topic of importance in core domains of human resource development (HRD) such as employee engagement, motivation, and personal development.
Catherine Bailey, Dr Ruth Yeoman, A. Madden, M. Thompson, Gary Kerridge   +4 more
semanticscholar   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Transformation through research? The AC+erm Project and Electronic Records Management [PDF]

, 2009
The article focuses on the three-year project being undertaken by Northumbria University in Northumbria, England and funded by the Arts & Humanities Research Council (ANRH) named as AC+erm. The AC+erm project is a qualitative study composed of three main
Childs, Sue, Hardiman, Rachel, McLeod, Julie   +2 more
core