Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The broadcasting dilemma: attitudes to the north: local political leadership: education and agriculture. [PDF]
, 1980 In the effort to measure Irish and British attitudes, Professor E. E. Davis, Richard Sinnott and their colleagues have elaborated techniques which cannot but impress. The administrative structure devised by the research team deserves to be greeted with
Institute of Public Administration
core
The quality of public administration performance is closely related to the issues of ethics in public administration [PDF]
, 2013 When discussing the quality of public administration performance, it is necessary to comprehend its direct relation to the issues of ethics in the sphere of public administration.
Nečadová, Věra
core +1 more source
Good Governance According to Islamic Perspective
Fiat Justisia, 2018 The objectives of the professional agencies must embody provisions that promote good governance and embrace values of integrity and accountability and seek support from the public and the government of the day to provide an independent view on all ...
Mohamad Ismail Bin Mohamad Yunus
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Challenges of Public Administration Accreditation in a Fragmented Institutional Setting: The Case of Europe [PDF]
, 2014 The paper is dealing with accreditation in higher education in Europe, based on observations in the European public administration accreditation field.
Reichard, Christoph
core +1 more source
Pengujian Perda dan Perdes Pasca Perubahan UU Pemda dan UU Desa
Jurnal Konstitusi, 2016 The development of contemporary public law (both in the field of constitutional law and administrative law) in Indonesia was marked by the strengthening of the internal settlement administration assertion as a means of testing the legal norms of both ...
Enrico Simanjuntak
doaj +1 more source
Growing ganja permission: a real gate-way for Thailand’s promising industrial crop?
Journal of Cannabis Research, 2022 The current revision to Thailand’s Narcotics Act (B.E. 2563) permits Thai corporations to produce cannabis (ganja) for therapeutic purposes, as well as conduct beneficial research and development in science and agriculture.
Sarana Rose Sommano +6 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Towards Excellence in Public Administration Education and Training: an African and South African Experience [PDF]
, 2014 Not only did globalization bring about profound changes to public administration worldwide, but it also challenged the implementation of the New Public Management (NPM) paradigm in terms of service delivery, posing the question whether public ...
Kroukamp, Hendri
core +1 more source