Results 71 to 80 of about 169,830,747 (289)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Accountability, Commercial State sponsored bodies, TD's interventions, European integration and the economy, Foreign policy, State and society.

, 1987
Administration is published four times a year. It is the journal of the Institute pf Public Administration, Ireland. The views expressed in it are the views of the contributors and not necessarily those of the Institute.
Institute of Public Administration (IPA)
core  

The State of E-Business in Slovenian Public Administration: The Case of Administrative Units [PDF]

, 2014
Over the last few years e-government in Slovenia has experienced very rapid development, with the latest EU surveys showing that Slovenia is among the most advanced member states in this field. However, the actual use of public e-services lags far behind
Vintar, Mirko, Jelenič, Mitja
core   +1 more source

Administrative Procedure as an Instrument of Public Administration

Вісник Академії праці, соціальних відносин і туризму. Серія: економіка, психологія та управління
The article examines the managerial dimension of administrative procedure as regulated by the Law of Ukraine "On Administrative Procedure". It is argued that administrative procedure, although traditionally perceived primarily as a procedural guarantee ...
Mykhailo Shtyka
doaj   +1 more source

الخروج عن مقتضى الواجب الوظيفي الموجب للمسؤوليَّة التأديبيَّة / Violation of Official Duties as Grounds for Disciplinary Liability [PDF]

مجلة البحوث الفقهیة والقانونیة
يقوم النشاط الإداري في الدولة على العديد من العناصر، ومن أهمها العنصر البشري ممثلًا في الموظف العام، فيؤدي الموظف العام عمله من خلال ارتباطه بما يسمَّى بالوظيفة العامة، وبمجرد نشوء العلاقة الوظيفية بين الشخص الطبيعي والسلطة الإدارية يصبح الموظف العام محلّ
عبدالرحمن بن زاحم شرار السلمي
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Reviewers' Report

, 2012
School of Public Administration (SPA) Reviewers' Report for Academic Program ReviewSchool of Public Administration (SPA)Reviewers' Report Academic Program ReviewSchool of Public Administration (SPA) - Academic Program ...
School of Public Administration (SPA), Reviewers' Report, Academic Program Review   +1 more
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Administration. Journal of the Institute of Public Administration of Ireland. 1980. Vol 28. No 4.

, 1980
Administration is published four times a year. It is the journal of the Institute of Public Administration Ireland. The views expressed in it are the views of the contributors, and not necessarily those of the Institute.
Litton, Frank, Institute of Public Administration (IPA)   +1 more
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source