Results 71 to 80 of about 1,120,414 (281)

Fixing FISA for Long War: Regulating Warrantless Surveillance in the Age of Terrorism [PDF]

, 2006
[Excerpt] “The English poet W.H. Auden once claimed that “Peeping Toms are never praised, like novelists or bird watchers, for the keenness of their observations.” Perhaps Auden would have modified his maxim had he lived in the age of terrorism.
Burton, Adam
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Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

AN ASSESSMENT OF CIVIL-MILITARY RELATIONS AND ITS IMPLICATIONS ON NIGERIA'S NATIONAL SECURITY

International Studies Journal, 2022
This paper attempts to trace the background to the sore relationship between the military and the civilian population. As this has continued to undermine the cordial civil-military relations in bordering on Nigeria's national security.
Uti Harrison Onyeka, Ubong Ituen Ituen
doaj  

State Anti-Crisis Management:the Age of the Formation of a New Model(Review of the Monograph of the Collective of the Authors of the MGIMO Russian Ministry of Foreign Affairs, under the General Editorship of Professor E. V. Okhotskiy «Public Administration in the Conditions of Crisis and Sanctionary Constraints: Domestic and Foreign Experience».M.: MGIMO-University Publishers, 2017. 889 p.)

Russian Journal of Legal Studies, 2018
The monograph «Public Administration in the Conditions of Crisis and Sanctionary Constraints: Domestic and Foreign Experience» touches upon the need for the operational development of concepts and mechanisms for studying, assessing, forecasting and sequential overcoming of actual crisis manifestations, especially the geopolitical crisis that began with
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

An Approach for Actions to Prevent Suicides on Commuter and Metro Rail Systems in the United States, MTI Report 12-33 [PDF]

, 2014
The primary goals of this report are to discuss measures to prevent suicides on commuter and metro rail systems, and to outline an approach for suicide prevention on rail systems.
Botha, Jan L., Kaur, Satnam, Neighbour, Marissa K.   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Challenges to democratic legitimacy, scrutiny, accountability in the UK national and local state [PDF]

, 2008
This article suggests that at national and local levels, the British state is seemingly incapable of solving multi-faceted and intractable social, economic and environmental problems alone. It is argued that new national and local governance arrangements,
Liddle, J
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