Results 91 to 100 of about 1,120,414 (281)

Working Papers as Federal Records: The Need for New Legislation to Preserve the History of National Policy [PDF]

open access: yes, 1994
This article deals with policy records at the front end of their lives; that is, preserving them from destruction by federal agencies in the decades immediately after their creation.
Schrag, Philip G.
core   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Legal Consequences of State Administrative Decisions That Violate Good Governance: An Analysis of Islamic Law and Positive Law on the SDGs

open access: yesProfetika
Objective: This study examines the legal consequences of State Administrative Decisions that violate the General Principles of Good Governance (Asas-Asas Umum Pemerintahan yang Baik/AUPB) as regulated in Law Number 30 of 2014 on State Administration ...
Ahmad Rosidi   +3 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

The Property Tax in a New Environment: Lessons from International Tax Reform Efforts [PDF]

open access: yes, 2004
Contemporary property tax reforms face the challenge of identifying the appropriate role for a tax on immobile physical assets in an economy ever more reliant on mobile and intangible factors.
Jane Malme, Joan Youngman
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Right to Information and Communication between Government and Citizens: Identifying Continuities and Discontinuities in the Practices of Turkey at the 10th Anniversary of the Law on Right to Information

open access: yesİletişim Kuram ve Araştırma Dergisi, 2016
The right to information as a form of right to petition is one of the cornerstones in the formation of the modern constitutional state and has important ties with the freedom of thought and expression as well as citizens’ right to ask their ...
Tuğba ASRAK HASDEMİR
doaj   +4 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Programmes in transition - between closure and start. Review of programme developments: Winter-Summer 2007 [PDF]

open access: yes, 2007
The past six months have seen a shift in emphasis from the 2000-2006 to the 2007-2013 programmes. Programme managers and other implementing organisations have not only been negotiating draft programmes for 2007-2013 with European Commission staff, but ...
Davies, S.S., Gross, T., IQ-Net (Funder)
core  

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