Results 81 to 90 of about 89,980 (338)

The use of geographical information in local authority planning departments. [PDF]

open access: yes, 1990
Information is perceived to be a vital resource by most organisations. In the case of local authority planning departments the majority of the information utilised has a geographical component. Technological advances in the last ten years have made it
Campbell, Heather J
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Administration: An examination of theory and its application to secondary public schools in Cyprus with particular reference to the role of principals [PDF]

open access: yes, 1995
The purpose of this study is to present in broad lines some of the basic theories of administration and to consequently examine the way administration is exercised in the secondary public schools of Cyprus to determine whether a better understanding of ...
Constantinidou, Ellada A.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Fighting fiscal corruption: The case of the Tanzania Revenue Authority [PDF]

open access: yes
Over the last decade several African countries have undertaken comprehensive reforms of their tax administrations, with the aims of increasing revenue and curbing corruption.
Odd-Helge Fjeldstad
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Challenges to democratic legitimacy, scrutiny, accountability in the UK national and local state

open access: yes, 2008
This article suggests that at national and local levels, the British state is seemingly incapable of solving multi-faceted and intractable social, economic and environmental problems alone. It is argued that new national and local governance arrangements,
Liddle, J
core  

AN ASSESSMENT OF CIVIL-MILITARY RELATIONS AND ITS IMPLICATIONS ON NIGERIA'S NATIONAL SECURITY

open access: yesInternational Studies Journal, 2022
This paper attempts to trace the background to the sore relationship between the military and the civilian population. As this has continued to undermine the cordial civil-military relations in bordering on Nigeria's national security.
Uti Harrison Onyeka, Ubong Ituen Ituen
doaj  

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