Results 81 to 90 of about 1,149,906 (199)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Pharmacist-led medication reviews: A scoping review of systematic reviews.

PLoS ONE
BackgroundMedication reviews aim to support patients who take medicines, and they are often led by pharmacists. There are different types of medication reviews undertaken in various settings. Previous research undertaken in 2015 found mixed evidence that
Miriam Craske, Wendy Hardeman, Nicholas Steel, Michael James Twigg   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Barriers and facilitators to the implementation and adoption of computerised clinical decision support systems: an overview of reviews

Systematic Reviews
Background The use of computerised clinical decision support systems (CDSSs) holds considerable potential in enhancing healthcare delivery by improving patient safety, practitioner performance, and patient outcomes. However, despite the numerous reported
Anna Katharina Böhm-Hustede, Johanna Sophie Lubasch, Anna Thalea Hoogestraat, Eike Buhr, Antje Wulff   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Telenursing as an Effective Ally for Improving Patient Outcomes in Diabetes? An Umbrella Review

Nursing Open
Aim To evaluate telenursing interventions' effectiveness in managing patients with diabetes mellitus. Design Overview of systematic reviews. Review Methods According to the PRISMA statement, we included studies published from 2005 to 2023 that evaluated ...
Marika Lo Monaco, Arianna Profeta, Salvatore Corrao   +2 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

A review of reviews exploring gender differences in sickness absence

Scandinavian Journal of Work, Environment & Health
OBJECTIVES: Long-term sickness absence is a risk factor for leaving the workforce, causing economic stress and deteriorating health. Women have higher rates of sickness absence compared to men in most, but not all, European countries.
Amber R McKenzie, Bethany Croak, Lise Gulli Brokjøb, Sharon A M Stevelink, Ira Madan, Beate Brinchmann, Wendy Nilsen, Karen Walker-Bone, Nils Abel Aars, Arnstein Mykletun   +9 more
doaj   +1 more source