Results 71 to 80 of about 9,148,999 (260)

The Applications of Mixtures of Normal Distributions in Empirical Finance: A Selected Survey [PDF]

open access: yes
This paper provides a selected review of the recent developments and applications of mixtures of normal (MN) distribution models in empirical finance. Once attractive property of the MN model is that it is flexible enough to accommodate various shapes of
Dinghai Xu
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

The nature and implications of the part-time employment of secondary school pupils [PDF]

open access: yes, 2004
This paper reports on the results of a review of existing measures of enterprising skills and attitudes. The review was undertaken firstly to identify definitions of enterprising skills and attitudes and secondly to inform the design of the questionnaire
Brownlow, Linda   +3 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Immunomodulation carried out by dietary fatty acids in experimental animals and humans

open access: yesGrasas y Aceites, 2000
Several studies have reported that fatty acids act as modulatory agents of immune response of experimental animals and humans. In this paper, we do and overview of the performed studies by using of unsaturated fatty acids and their influence on several ...
M. A. de Pablo Martínez   +4 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Early childhood transitions research: A review of concepts, theory, and practice’ Working Paper 48 [PDF]

open access: yes, 2008
Chapter 1 begins by outlining developmental concepts which underpin transition themes, in particular those associated with the theories of Jean Piaget and other ‘stage’ theorists.
Gina, Crivello   +2 more
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Effect of lipid damages on processed fish quality.

open access: yesGrasas y Aceites, 1999
Marine species constitute a food group recognised as being easily damaged during the technological processing. Between the different damage pathways that can act on a marine food, a big attention has been given to the oxidation ability of lipids, as a ...
Santiago P. Augbourg
doaj   +1 more source

Irrigation management research in Sri Lanka: A review of selected literature. Occasional paper. Occasional paper [PDF]

open access: yes
Irrigation management / Research / Irrigation systems / Rehabilitation / Financing / Resource management / Policy / Farmer participation / Farmer-agency interactions / Sri ...
Martin, E., Merrey, D. J., Rao, P. S.
core  

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