Results 81 to 90 of about 9,148,999 (260)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Grasas y Aceites, 1995 This review focuses on the mechanisms of formation of oxysterols and factors that influence on their formation and content in foods. Aspects of growing interest because of the numerous biological effects reported for these compounds.
F. Guardiola +3 more
doaj +1 more source
Financial transaction tax: review and assessment [PDF]
We explore whether a Financial Transactions Tax (FTT) is likely to correct the market failures that have contributed to the financial crisis, to what extent FTT succeeds in raising revenues, and how the FTT compares to alternative taxes in terms of ...
Adam Elbourne +4 more
core
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Extraction and clean-up of pesticides from fatty samples
Grasas y Aceites, 2000 The extraction of pesticides from fatty samples is a problem extensively studied. In this paper, the main techniques for the extraction of pesticides from fatty samples are reviewed.
M. López-Mesas, M. Crespi
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Foundations for measuring equality: A discussion paper for the Equalities Review [PDF]
The Equalities Review is an independent panel set up by the UK government in 2005 to investigate the persistence of social inequalities and to make recommendations for the development of a unified Commission for Equality and Human Rights.
Tania Burchardt
core
A geometrical analysis of the field equations in field theory
, 2001 In this review paper we give a geometrical formulation of the field equations in the Lagrangian and Hamiltonian formalisms of classical field theories (of first order) in terms of multivector fields.
Echeverría-Enríquez, A. +2 more
core +3 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
How to review a scientific paper
Zaštita Materijala, 2017 A review process is a key factor which ensures reliable and accurate presentation of new, useful, and original scientific knowledge to the public. Despite of many shortcomings which this evaluation of scientific work has, it is still an indispensable ...
Aleksandar Dekanski +2 more
doaj +1 more source