Results 221 to 230 of about 14,475,028 (324)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

User perceptions of RBI-approved P2P digital lending apps: an NLP, machine learning, and deep learning approach. [PDF]

Front Artif Intell
Sekhar KR, Saheb SS.
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

A rapid and systematic review of the clinical effectiveness and cost-effectiveness of topotecan for ovarian cancer

Health Technology Assessment, 2001
C. Forbes, L. Shirran, A.-M. Bagnall, S. Duffy, G. ter Riet   +4 more
doaj   +1 more source

A systematic meta-review of interventions to prevent and manage delirium in the Intensive Care Unit: Part 1 - Pharmacological interventions. [PDF]

Crit Care
L Jones K, Kundakci B, Booth A, Falzon L, Gibbison B, Pufulete M, OPTIC consortium.   +6 more
europepmc   +1 more source

Scoping reviews.

Physiotherapy, 2019
M. Harms, V. Goodwin
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Effect of minimal intervention on carious lesions in primary teeth. An Umbrella review. [PDF]

Front Dent Med
Padilla-Cáceres TC, Arbildo-Vega HI, Mamani-Cori V, Caballero-Apaza LM, Cruzado-Oliva FH, Farje-Gallardo CA, Marroquín-Soto C, Aguirre-Ipenza R, Vásquez-Rodrigo H, Luján-Valencia SA, Meza-Málaga JM, Castillo-Cornock TB, Coronel-Zubiate FT.   +12 more
europepmc   +1 more source

Reflections: Reviews, reviewers [PDF]

Journal of Bodywork and Movement Therapies, 2015
openaire   +2 more sources