Results 111 to 120 of about 1,522,172 (292)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Dolor óseo inducido por cáncer metastásico: fisiopatología y tratamiento

Acta Médica Costarricense, 2004
Se estima que de un 60 a 84% de los pacientes con cáncer desarrollan metástasis óseas. De estos un 70% experimentan síndrome s dolorosos de difícil manejo, de los cuales un 50% muere sin un adecuado alivio del dolor con una pobre calidad de vida.
Isaías Salas-Herrera, Luis Carlos Huertas-Gabert   +1 more
doaj  

Pre‐Diagnostic Features of Multiple Sclerosis in a Diverse UK Cohort: A Nested Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Many patients with Multiple Sclerosis (MS) experience nonspecific symptoms prior to diagnosis. This period—the 'MS prodrome'—has been described in socio‐economically homogeneous cohorts to date. It remains unclear to what extent events prior to an MS diagnosis differ according to social determinants of health. Methods We conducted a
Pooja Tank, Benjamin M. Jacobs, Jonathan Bestwick, Ruth Dobson   +3 more
wiley   +1 more source

The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes.

Blood, 2009
J. Vardiman, J. Thiele, D. Arber, R. Brunning, M. Borowitz, A. Porwit, N. Harris, M. L. Le Beau, E. Hellström-Lindberg, A. Tefferi, C. Bloomfield   +10 more
semanticscholar   +1 more source

Genetic Modifiers of Parkinson's Disease: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the associations of LRRK2 p.G2019S, GBA1 p.N409S, polygenic risk scores (PRS), and APOE E4 on PD penetrance, risk, and symptoms. Methods We conducted a US‐based observational case–control study using data from the 23andMe Inc. and Fox Insight Genetic Substudy (FIGS) databases.
Matthew J. Kmiecik, Michael V. Holmes, Pierre Fontanillas, Giulietta M. Riboldi, Ruth B. Schneider, Jingchunzi Shi, Anna Guan, Susana Tat, Steven Micheletti, Keaton Stagaman, Josh Gottesman, David A. Hinds, Joyce Y. Tung, 23andMe Research Team, Stella Aslibekyan, Lucy Norcliffe‐Kaufmann   +15 more
wiley   +1 more source

Selección de artículos de alto impacto en el campo de la salud ocupacional.

Revista Colombiana de Salud Ocupacional, 2011
En consonancia con nuestro propósito de fortalecer la producción intelectual en las diferentes áreas de la Salud Ocupacional, presentamos a ustedes una selección de los artículos científicos originales más recientes y de mayor impacto.
Augusto Valderrama Aguirre
doaj  

Toxoplasmosis cerebral asociado a VIH-SIDA: Revisión de literatura y reporte de un caso

, 2017
Zairie Niguelie Cawich, Santiago Hernández Bojorge, Olíz Solís Carbajal, Clara González Moncada   +3 more
openalex   +2 more sources

Una revisión sistemática de los patógenos virales y bacterianos de aves silvestres en Chile [PDF]

, 2020
Daniel González‐Acuña, Sebastián Llanos‐Soto   +1 more
openalex   +1 more source

A Revision of Bloom's Taxonomy: An Overview

, 2002
D. Krathwohl
semanticscholar   +1 more source

Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA

Nature Genetics, 1999
R. Andrews, I. Kubacka, P. Chinnery, R. Lightowlers, D. Turnbull, N. Howell   +5 more
semanticscholar   +1 more source